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Rapid separation of fresh fission products

  • D. E. Dry
  • E. Bauer
  • L. A. Petersen
Article

Summary

A novel radiochemical separation for <Superscript>48</Superscript>V radiotracer in no-carrier-added (NCA) form, via proton irradiation on Ti targets of natural isotopic composition has been developed. Metallic Ti targets irradiated with 21 MeV proton beam energy was submitted to a selective radiochemical separation consisting of an alkaline fusion-precipitation step, followed by column Chelex-100 chromatographic purification. Very high specific activity <Superscript>48</Superscript>V, at levels of hundreds MBq<Superscript> .</Superscript>&micro;g<Superscript>-1</Superscript> was prepared. Chemical analysis of radiotracer was carried out by ET-AAS and INAA. The decontamination factor from Ti target was 5<Superscript> .</Superscript> 10<Superscript>5</Superscript>, with an overall radiochemical yield for <Superscript>48</Superscript>V larger than 90&percnt;. The NCA <Superscript>48</Superscript>V has used for labeling a range of chemical forms of V(III, IV, V) and applied in the study of metabolic behavior of different chemical forms in in-vivo and in-vitro experiments on rats and cell cultures.

Keywords

INAA Proton Beam Fission Product High Specific Activity Radiochemical Yield 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag/Akad&#233;miai Kiad&#243; 2005

Authors and Affiliations

  • D. E. Dry
    • 1
  • E. Bauer
    • 2
  • L. A. Petersen
    • 3
  1. 1.Chemistry Division, Isotope and Nuclear Chemistry, C-INC, Los Alamos National Laboratory
  2. 2.Chemistry Division, Isotope and Nuclear Chemistry, C-INC, Los Alamos National Laboratory
  3. 3.New Mexico Institute of Mining and Technology

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