Journal of Polymer Research

, 25:45 | Cite as

Self-assembly nucleic acid-based biopolymers: learn from the nature

  • Pitchaya Pakornpadungsit
  • Wirasak Smitthipong
  • Arkadiusz Chworos
Part of the following topical collections:
  1. Topical Collection on Bio-Based Polymers


This review highlights the recent developments in nucleic acid-based based materials for biomedical applications and functional devices. DNA and RNA are anionic macromolecules composing sugar-phosphate backbone, which usually structure as rod-like double helix with base pair stacking. Electrostatic interactions are the main components in the complex formed between anionic nucleic acid and cationic molecule. These nucleic acid-based biopolymers have significant potential as functional materials for drug delivery, biosensors, and a scaffold for many biodegradable materials.


DNA RNA Self-assembly Electrostatic interaction Supramolecular material Functional material 



This work is supported by Kasetsart University Research and Development Institute (KURDI), Kasetsart University, Thailand. The authors would like to gratefully acknowledge Professor Matthew Tirrell from University of Chicago for all the supports.


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Copyright information

© Springer Science+Business Media B.V., part of Springer Nature 2018

Authors and Affiliations

  • Pitchaya Pakornpadungsit
    • 1
  • Wirasak Smitthipong
    • 1
    • 2
  • Arkadiusz Chworos
    • 3
  1. 1.Specialized Center of Rubber and Polymer Materials for Agriculture and Industry (RPM), Department of Materials Science, Faculty of ScienceKasetsart UniversityBangkokThailand
  2. 2.Office of Natural Rubber Research ProgramThe Thailand Research Fund (TRF)BangkokThailand
  3. 3.Centre of Molecular and Macromolecular StudiesPolish Academy of SciencesLodzPoland

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