Solution Properties of Azidokojatoiron(III) Complexes

  • Rastislav Šípoš
  • Jozef Šima
  • Mário Izakovič
  • Pavol Tarapčík


The formation of iron(III) complexes with chelating azidokojate anions L was investigated in aqueous solutions as a function of the pH and the c(Fe3+):c(HL) molar ratio. Based on the stability constants, the distribution among the above complexes, [Fe(H2O)6]3+, and [Fe(H2O)5(OH)]2+ were calculated in solutions of various compositions. The complexes are redox stable in aqueous solutions both in the dark and in visible laboratory light. Properties of the investigated azidokojic acid and its iron(III) complexes are compared with those required for therapeutic applications as alternative iron chelators.


Stability constants Speciation Iron(III) complexes Azidokojic acid 


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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Rastislav Šípoš
    • 1
  • Jozef Šima
    • 1
  • Mário Izakovič
    • 1
  • Pavol Tarapčík
    • 2
  1. 1.Department of Inorganic ChemistrySlovak Technical UniversityBratislavaSlovakia
  2. 2.Department of Analytical ChemistrySlovak Technical UniversityBratislavaSlovakia

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