Molecular and crystal structure of 2,4-diethoxycarbonyl-5-hydroxy-5-methyl-3-phenyl-N-(3-chlorophenyl)-1-cyclohexenylamine
- 40 Downloads
Arylamination of 2,4-diethoxycarbonyl-5-hydroxy-5-methyl-3-phenylcyclohexanone affords 2,4-diethoxycarbonyl-5-hydroxy-5-methyl-3-phenyl-N-(3-chlorophenyl)-1-cyclohexenylamine. A distorted semi-chair conformation with psedoequatorial orientation of all substituents except the pseudoaxial OH-group is established based on the spectral and single crystal XRD data. The presence of an intramolecular N-H...O=C hydrogen bond is noted.
KeywordsX-ray structural analysis enaminoesters cyclohexenes
Unable to display preview. Download preview PDF.
- 1.V. V. Sorokin, A. V. Grigoriev, A. K. Ramzanov, and A. P. Kriven’ko, J. Org. Khim., 36, No. 6, 815–818 (2000).Google Scholar
- 2.G. M. Sheldrick, SHELX-97, 97–2, Univ. Götingen, Germany (1997).Google Scholar
- 3.É. A. Grigor’eva, A. P. Kriven’ko, V. V. Sorokin, et al, Izv. Vyssh. Uchebn. Zaved., Khim. Khim. Techn., 47, No. 4, 108–111 (2004).Google Scholar
- 4.A. P. Kriven’ko, A. G. Golikov, A. V. Grigor’ev, and V. V. Sorokin, Zh. Org. Khim., 36, No. 8, 1152–1155 (2000).Google Scholar