Molecular and crystal structure of 2,4-diethoxycarbonyl-5-hydroxy-5-methyl-3-phenyl-N-(3-chlorophenyl)-1-cyclohexenylamine
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Arylamination of 2,4-diethoxycarbonyl-5-hydroxy-5-methyl-3-phenylcyclohexanone affords 2,4-diethoxycarbonyl-5-hydroxy-5-methyl-3-phenyl-N-(3-chlorophenyl)-1-cyclohexenylamine. A distorted semi-chair conformation with psedoequatorial orientation of all substituents except the pseudoaxial OH-group is established based on the spectral and single crystal XRD data. The presence of an intramolecular N-H...O=C hydrogen bond is noted.
KeywordsX-ray structural analysis enaminoesters cyclohexenes
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