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Applying Under-Sampling Techniques and Cost-Sensitive Learning Methods on Risk Assessment of Breast Cancer

  • Jia-Lien Hsu
  • Ping-Cheng Hung
  • Hung-Yen Lin
  • Chung-Ho Hsieh
Non-invasive Diagnostic Systems
Part of the following topical collections:
  1. Systems-Level Quality Improvement

Abstract

Breast cancer is one of the most common cause of cancer mortality. Early detection through mammography screening could significantly reduce mortality from breast cancer. However, most of screening methods may consume large amount of resources. We propose a computational model, which is solely based on personal health information, for breast cancer risk assessment. Our model can be served as a pre-screening program in the low-cost setting. In our study, the data set, consisting of 3976 records, is collected from Taipei City Hospital starting from 2008.1.1 to 2008.12.31. Based on the dataset, we first apply the sampling techniques and dimension reduction method to preprocess the testing data. Then, we construct various kinds of classifiers (including basic classifiers, ensemble methods, and cost-sensitive methods) to predict the risk. The cost-sensitive method with random forest classifier is able to achieve recall (or sensitivity) as 100 %. At the recall of 100 %, the precision (positive predictive value, PPV), and specificity of cost-sensitive method with random forest classifier was 2.9 % and 14.87 %, respectively. In our study, we build a breast cancer risk assessment model by using the data mining techniques. Our model has the potential to be served as an assisting tool in the breast cancer screening.

Keywords

Breast cancer Cost-sensitive learning Sampling 

Notes

Acknowledgments

Financial support for this study was provided in part by a grant from the National Science Council, Taiwan, under Contract No. NSC-102-2218-E-030-002. The funding agreement ensured the authors’ independence in designing the study, interpreting the data, writing, and publishing the report.

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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • Jia-Lien Hsu
    • 1
  • Ping-Cheng Hung
    • 1
  • Hung-Yen Lin
    • 1
  • Chung-Ho Hsieh
    • 2
  1. 1.Department of Computer Science and Information EngineeringFu Jen Catholic UniversityNew Tapei CityRepublic of China
  2. 2.Department of General SurgeryShin Kong Wu Ho-Su Memorial HospitalTaipeiRepublic of China

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