Journal of Medical Systems

, Volume 36, Issue 4, pp 2071–2083 | Cite as

Application of Intelligent Systems in Asthma Disease: Designing a Fuzzy Rule-Based System for Evaluating Level of Asthma Exacerbation

  • Maryam Zolnoori
  • Mohammad Hossein Fazel Zarandi
  • Mostafa Moin


This paper discusses the capacities of artificial intelligence in the process of asthma diagnosing and asthma treatment. Developed intelligent systems for asthma disease have been classified in five categories including diagnosing, evaluating, management, communicative facilities, and prediction. Considering inputs, results, and methodologies of the systems show that by focusing on meticulous analysis of quality of life as an input variable and developing patient-based systems, under-diagnosing and asthma morbidity and mortality would decrease significantly. Regard to the importance of accurate evaluation in accurate prescription and expeditious treatment, the methodology of developing a fuzzy expert system for evaluating level of asthma exacerbation is presented in this paper too. The performance of this system has been tested in Asthma, Allergy, and Immunology Center of Iran using 25 asthmatic patients. Comparison between system’s results and physicians’ evaluations using Kappa coefficient (K) reinforces the value of K = 1. In addition this system assigns a degree in gradation (0–10) to every patient representing the slight differences between patients assigned to a specific category.


Intelligent systems Fuzzy Asthma Asthma exacerbation 


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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Maryam Zolnoori
    • 1
    • 2
  • Mohammad Hossein Fazel Zarandi
    • 3
  • Mostafa Moin
    • 4
  1. 1.Mathematic and Informatics Group, Academic Center for Education, Culture and Research (ACECR)Tarbiat Modares UniversityTehranIran
  2. 2.Department of Information Technology ManagementTarbiat Modares UniversityTehranIran
  3. 3.Department of Industrial EngineeringAmirkabir University of TechnologyTehranIran
  4. 4.Immunology, Asthma and Allergy Research InstituteTehran University of Medical SciencesTehranIran

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