A Study of Heating Duration and Scanning Path in Focused Ultrasound Surgery
A conventional method of avoiding normal tissue overheating during focused ultrasound surgery (FUS) is to apply equal heating duration for each sonication in between cooling intervals. However, this method is time-consuming and expensive. A novel method with unequal heating duration in different scanning paths without cooling intervals was investigated in this paper. This method was compared with the conventional method through the ablation of a 10 × 10 cm2 target. The simulation results indicated that the new method was able to reduce treatment time by more than 50%, with higher than 95% coverage index, and more uniform thermal dose distribution. The method was further verified through the ablation of a circular lesion. Ex vivo experiments were also performed to confirm the simulation results. Both simulation and experimental results have proven that the new method can increase heating efficiency, and are a promising new approach in FUS.
KeywordsFocused ultrasound surgery Unequal heating duration Scanning path Heating efficiency
This study was supported by the National Natural Science Foundation of China (No. 30800246), the Ph.D. Programs Foundation of Ministry of Education of China (No. 20070248082), and Shanghai Key Technologies R&D Program of China (No. 09441900500).
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