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Volatilities of codons and its application in similarity analysis of biological sequences

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Volatilities of codons provide us a new way to characterize codons. In this article, we propose a new method measuring volatilities of codons base on the physics–chemical distances between amino acids and mutation frequencies between codons, then by which, we give a new graphical representation scheme for codon sequences. Finally, in order to show the effectiveness of our scheme, we analyze similarity among the coding codon sequences of exon 1 of beta-globin gene of human and those of other 10 species, find the result is consistent with those shown in the literature.

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Authors and Affiliations

  1. Department of Applied Mathematics, Dalian University of Technology, Dalian, 116024, People’s Republic of China

    Yi Zhang

  2. Department of Applied Mathematics and College of Advanced Science and Technology, Dalian University of Technology, Dalian, 116024, People’s Republic of China

    Jun Wang

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  1. Yi Zhang
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  2. Jun Wang
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Correspondence to Jun Wang.

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Zhang, Y., Wang, J. Volatilities of codons and its application in similarity analysis of biological sequences. J Math Chem 43, 864–873 (2008). https://doi.org/10.1007/s10910-007-9235-9

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  • DOI: https://doi.org/10.1007/s10910-007-9235-9

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