A Turn‐on Fluorescent Probe for the Discrimination of Cys/Hcy and GSH With Dual Emission Signals

Abstract

In this paper, we successfully synthesized a simple and versatile fluorescent probe. This probe was not only easily prepared with a high yield, but also showed rapid selective and sensitive responses for Cys/Hcy and GSH. The probe can be used as a naked-eye detector for Cys/Hcy and GSH from other analytes. As a fluorescent sensor, it can be used to simultaneously detect and discriminate Cys/Hcy from GSH with two fluorescent emission signals without spectral crosstalk.

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Data Availability

All the data are available.

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Acknowledgements

This work was supported by the National Natural Science Foundation of China (41867053), the Jiangxi Provincial Natural Science Foundation (20202BAB215003) and the Entrepreneurship training program for College Students (202011318039X).

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Contributions

Yanhua Wang: Investigation, Writing-original draft. Guowei Lu: Synthesis, Investigation. Yayi Tu: Writing-review & editing, Supervision, Validation. Shouzhi Pu: Project administration, Funding acquisition.

Corresponding authors

Correspondence to Yayi Tu or Shouzhi Pu.

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Wang, Y., Lu, G., Tu, Y. et al. A Turn‐on Fluorescent Probe for the Discrimination of Cys/Hcy and GSH With Dual Emission Signals. J Fluoresc 31, 599–607 (2021). https://doi.org/10.1007/s10895-021-02684-6

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Keywords

  • Cysteine
  • Homocysteine
  • Glutathione
  • Fluorescent sensor
  • Dual emission