Journal of Fluorescence

, Volume 22, Issue 1, pp 391–395 | Cite as

A New Highly Sensitive and Selective Fluorescent Cadmium Sensor

  • Priyanka Goswami
  • Diganta Kumar Das
Original Paper


Condensation product (L) of salicylaldehyde and semicarbazide behaves as a fluorescent sensor for Cd2+ ion, in 1:1 DMSO:H2O, over Mn2+, Fe2+, Ni2+, Co2+, Cu2+, Pb2+ and Hg2+ ions. The emission peak of L at λmax = 520 nm, on excitation with 420 nm wavelength photons, showed an enhancement in intensity of ca 60-fold when interacted with Cd2+ ion. The intensity was however found to remain unaltered when interacted with metal ions—Mn2+, Fe2+, Ni2+, Co2+, Cu2+, Pb2+ and Hg2+. The intensity increases by approximately 20 fold on interaction with Zn2+ ion. The increase in the fluorescent peak can be explained on the basis of photo induced electron transfer (PET) mechanism. A 1:1 complexation between Cd2+ and L with log β = 4.25 has been proved.


Cadmium Salicylaldehyde Semicarbazide Fluorescence Sensor Photo induced electron transfer (PET) 



UGC and DST, New Delhi are thanked for SAP and FIST respectively. PG thanks UGC for fellowship under RFSMS.


  1. 1.
    Lee HN, Xu ZC, Kim SK, Swamy KMK, Kim Y, Kim SJ, Yoon JY (2007) Pyrophosphate -selective fluorescent chemosensor at physiological pH:Formation of a unique excimer upon addition of pyrophosphate. J Am Chem Soc 129:3828–3829PubMedCrossRefGoogle Scholar
  2. 2.
    Wang JB, Qian XH (2006) Two regioisomeric and exclusively selective Hg(II) sensor molecules composed of a naphthalimide fluorophore and an o-phenylenediamine derived triamide receptor. Chem Commun 109–111.Google Scholar
  3. 3.
    Komatsu K, Urano Y, Kojima P, Nagano TJ (2007) Development of an iminocoumarin- based zinc sensor suitable for ratiometric fluorescence imaging of neuronal zinc. J Am Chem Soc 129:13447–13454PubMedCrossRefGoogle Scholar
  4. 4.
    Jackson T, MacGillivray A (1993) In Accounting for Cadmium. Stockholm Environment Institute, LondonGoogle Scholar
  5. 5.
    Cadmium and Compounds, US Environmental Protection Acency (2001)Google Scholar
  6. 6.
    Dobson S (1992) Cadmium-Environmental Aspects World health Organisation:GenevaGoogle Scholar
  7. 7.
    Butcher SS, Chalrson RJ, Orians GH, Wolfe GV (1992) Eds Academic: London 317Google Scholar
  8. 8.
    Luo HY, Jiang JH, Zhang XB, Li CY, Shen GL, Yu RQ (2007) Synthesis of porphyrin -appended terpyridine as a chemosensor for cadmium based on fluorescent enhancement. Talanta 72:575–581PubMedCrossRefGoogle Scholar
  9. 9.
    Zhang J, Campbell RE, Ting AY, Tisen RY (2002) Creating New Fluorescent Probes for Cell Biology. Nat Rev Mol Cell Biol 3:906–918PubMedCrossRefGoogle Scholar
  10. 10.
    Lu C, Xu Z, Cui J, Zhang R, Qian XJ (2007) Ratiometric and highly selective fluorescent sensor for cadmium under physiololgical pH range: a new strategy to discriminate cadmium from zinc. Org Chem 72:3554–3557CrossRefGoogle Scholar
  11. 11.
    Gunnlaugsson T, Lee TC, Parkesh R (2003) Cd(II) Sensing in Water Using Novel Fluorescent Chemosensors. Org Lett 5:4065–4068PubMedCrossRefGoogle Scholar
  12. 12.
    Tang X, Peng X, Dou W, Mao J, Zheng J, Qin W, Liu W, Chang J, Yao X (2008) Design of a semirigid molecule as a selective fluorescent chemosensor for recognition of Cd(II). Org Lett 10:3653–3656PubMedCrossRefGoogle Scholar
  13. 13.
    Bronson RT, Michaelis DJ, Lamb RD, Hesseini GA, Farnsworth PB, Linford MR, Izatt RM, Brandshaw JS, Savage PB (2005) Efficient immobilization of a cadmium chemosensor in a thin film: Generation of a cadmium sensor prototype. Org Lett 7:1105–1108PubMedCrossRefGoogle Scholar
  14. 14.
    Xue L, Liu C, Jiang H (2009) Highly sensitive and selective fluorescent sensor for distinguishing cadmium from zinc ions in aqueous media. Org Lett 11:1655–1658PubMedCrossRefGoogle Scholar
  15. 15.
    Komatsu K, Kikuchi K, Kojima H, Urano Y, Nagano T (2005) Selective zinc sensor molecules with various affinities for Zn2+, revealing dynamics and regional distribution of synaptically released Zn2+ in hippocampal slices. J Am Chem Soc 127:10197–10204PubMedCrossRefGoogle Scholar
  16. 16.
    Nolan EM, Ryu JW, Jaworski J, Feazell RP, Sheng M, Lippard SJ (2006) Zinspy sensors with enhanced dynamic range for imaging neuronal cell zinc uptake and mobilization. J Am Chem Soc 128:15517–15528PubMedCrossRefGoogle Scholar
  17. 17.
    Henary MM, Wu YG, Fahrni CJ (2004) Zinc (II) selective ratiometric fluorescent sensors based on inhibition of excited -state intramolecular proyon transfer. Chem Eur J 10:3015–3025PubMedCrossRefGoogle Scholar
  18. 18.
    Gunnlaugsson T, Lee TC, Parkesh R (2004) Highly selective fluorescent chemosensors for cadmium in water. Tetrahedron 60:11239–11249CrossRefGoogle Scholar
  19. 19.
    Zhou Y, Xiao Y, Qian X (2008) A highly selective Cd2+ sensor of naphthyridine fluorescent enhancement and red-shift by the synergistic action of forming binuclear complex. Tetrahedron Lett 49:3380–3384CrossRefGoogle Scholar
  20. 20.
    Soibinet M, Souchon V, Leray I, Valeur B (2008) Rhod-5 N as a Fluorescent Molecular Sensor of Cadmium(II) Ion. J Fluorescence 18:1077–1082CrossRefGoogle Scholar
  21. 21.
    Costero AM, Gil S, Sanchis J, Peransi S, Sanz V, Williams JAG (2004) Conformationally regulated fluorescent sensors.Study of the selectivity in Zn2+ versus Cd2+ sensing. Tetrahedron 60:6327–6334CrossRefGoogle Scholar
  22. 22.
    Kulatilleke CP, Silva SA, Eliav Y (2006) A coumarin based fluorescent photoinduced electron transfer cation sensor. Polyhedron 25:2593–2596CrossRefGoogle Scholar
  23. 23.
    Goswami P, Baruah S, Das DK (2010) 2,7-Dichlorofluorescein, a fluorescent sensor to detect Cd2+ over Na+, K+, Ca2+, Cu2+, Ni2+ and Zn2+. Indian J Chem 49A:1617–1620Google Scholar

Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Department of ChemistryGauhati UniversityGuwahatiIndia

Personalised recommendations