The Role of Social and Cognitive Processes in the Relationship Between Fear Network and Psychological Distress Among Parents of Children Undergoing Hematopoietic Stem Cell Transplantation
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The current study examined whether cognitive and social processing variables mediated the relationship between fear network and depression among parents of children undergoing hematopoietic stem cell transplant (HSCT). Parents whose children were initiating HSCT (N = 179) completed survey measures including fear network, Beck Depression Inventory, cognitive processing variables (positive reappraisal and self-blame) and social processing variables (emotional support and holding back from sharing concerns). Fear network was positively correlated with depression (p < .001). Self-blame and holding back emerged as individual partial mediators in the relationship between fear network and depression. Together they accounted for 34.3 % of the variance in the relationship between fear network and depression. Positive reappraisal and emotional support did not have significant mediating effects. Social and cognitive processes, specifically self-blame and holding back from sharing concerns, play a negative role in parents’ psychological adaptation to fears surrounding a child’s HSCT.
KeywordsPediatric hematopoietic stem cell transplant Fear Psychological adaptation Parents
This research was supported by Grant (R01 CA127488) awarded to (second author) from the National Institute of Health (NIH). The authors wish to thank (research assistants names) for their assistance in collection of study data, and (project managers names) for project management. We would like to extend our appreciation to the transplant teams and the parent caregivers who participated in this study.
Conflict of Interest
Shannon Myers Virtue, Sharon Manne, Laura Mee, Abraham Bartell, Stephen Sands, Pamela Ohman-Strickland, and Tina Marie Gajda declare that they have no conflict of interest.
Human and Animal Rights and Informed Consent
All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation of (name of participating institutions) and with the Helsinki Declaration of 1975, as revised in 2000. Informed consent was obtained for all participants for being included in this study.
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