The Role of Social and Cognitive Processes in the Relationship Between Fear Network and Psychological Distress Among Parents of Children Undergoing Hematopoietic Stem Cell Transplantation
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The current study examined whether cognitive and social processing variables mediated the relationship between fear network and depression among parents of children undergoing hematopoietic stem cell transplant (HSCT). Parents whose children were initiating HSCT (N = 179) completed survey measures including fear network, Beck Depression Inventory, cognitive processing variables (positive reappraisal and self-blame) and social processing variables (emotional support and holding back from sharing concerns). Fear network was positively correlated with depression (p < .001). Self-blame and holding back emerged as individual partial mediators in the relationship between fear network and depression. Together they accounted for 34.3 % of the variance in the relationship between fear network and depression. Positive reappraisal and emotional support did not have significant mediating effects. Social and cognitive processes, specifically self-blame and holding back from sharing concerns, play a negative role in parents’ psychological adaptation to fears surrounding a child’s HSCT.
KeywordsPediatric hematopoietic stem cell transplant Fear Psychological adaptation Parents
This research was supported by Grant (R01 CA127488) awarded to (second author) from the National Institute of Health (NIH). The authors wish to thank (research assistants names) for their assistance in collection of study data, and (project managers names) for project management. We would like to extend our appreciation to the transplant teams and the parent caregivers who participated in this study.
Conflict of Interest
Shannon Myers Virtue, Sharon Manne, Laura Mee, Abraham Bartell, Stephen Sands, Pamela Ohman-Strickland, and Tina Marie Gajda declare that they have no conflict of interest.
Human and Animal Rights and Informed Consent
All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation of (name of participating institutions) and with the Helsinki Declaration of 1975, as revised in 2000. Informed consent was obtained for all participants for being included in this study.
- Barrera, M., & Ainlay, S. L. (1983). The structure of social support: A conceptual and empirical analysis. Journal of Community Psychology, 11(2), 133–143.Google Scholar
- Beck, A. T., Steer, R. A., & Brown, G. K. (1996). Manual for the Beck depression inventory-II. San Antonio, TX: Psychological Corporation.Google Scholar
- DuHamel, K. N., Manne, S., Nereo, N., Ostroff, J., Martini, R., Parsons, S., … Redd, W. H. (2004). Cognitive processing among mothers of children undergoing bone marrow/stem cell transplantation. Psychosomatic Medicine, 66, 92–103.Google Scholar
- DuHamel, K. N., Rini, C., Austin, J., Ostroff, J., Parsons, S., Martini, R., … Manne, S. (2007). Optimism and life events as predictors of fear appraisals in mothers of children undergoing hematopoietic stem cell transplantation. Psychooncology, 16, 821–833.Google Scholar
- Dunkel-Schetter, C. (1984). Social support and cancer: Findings based on patient interviews and their implications. Journal of Social Issues, 40(4), 77–98.Google Scholar
- Hayes, A. F. (2013). Introduction to mediation, moderation, and conditional process analysis: A regression-based approach. New York, NY: Guilford Press.Google Scholar
- Kazak, A. E. (1998). Posttraumatic distress in childhood cancer survivors and their parents. Pediatric Blood & Cancer, 30(S1), 60–68.Google Scholar
- Kronenberger, W. G., Carter, B. D., Edwards, J., Morrow, C., Stewart, J., & Sender, L. (1998). Psychological adjustment of mothers of children undergoing bone marrow transplantation: The role of stress, coping, and family factors. Children’s Health, 27(2), 77–95.Google Scholar
- Manne, S. L., Badr, H., Zaider, T., Nelson, C., & Kissane, D. (2010). Cancer-related communication, relationship intimacy, and psychological distress among couples coping with localized prostate cancer. Journal of Cancer Survivorship, 4, 74–85.Google Scholar
- Manne, S., Dougherty, J., Veach, S., & Kless, R. (1999). Hiding worries from one’s spouse: Protective buffering among cancer patients and their spouses. Cancer Research Therapy and Control, 8, 175–188.Google Scholar
- Manne, S., DuHamel, K., Nereo, N., Ostroff, J., Parsons, S., Martini, R. … Redd, W. H. (2002). Predictors of PTSD in mothers of children undergoing bone marrow transplantation: The role of cognitive and social processes. Journal of Pediatric Psychology, 27(7), 607–617.Google Scholar
- Manne, S., DuHamel, K., Ostroff, J., Parsons, S., Marini, D. R., Williams, S. E., … Redd, W. H. (2003). Coping and the course of mother’s depressive symptoms during and after pediatric bone marrow transplant. Journal of the American Academy of Child and Adolescent Psychiatry, 42(9), 1055–1068.Google Scholar
- Manne, S., DuHamel, K., Ostroff, J., Parsons, S., Marini, D. R., Williams, S. E., … Redd, W. H. (2004). Anxiety, depression, and posttraumatic stress disorders among mothers of pediatric survivors of hematopoietic stem cell transplantation. Pediatrics, 113(6), 1700–1708.Google Scholar
- Manne, S., Nereo, N., DuHamel, K., Ostroff, J., Parsons, S., & Martini, D. R. (2001). Anxiety and depression in mothers of children undergoing bone marrow transplant: Symptom prevalence and use of the Beck depression and Beck anxiety inventories as screening instruments. Journal of Consulting and Clinical Psychology, 69(9), 1037–1047.PubMedCrossRefGoogle Scholar
- Myers, S., Manne, S. L., Kissane, D. W., Ozga, M., Kashy, D. A., Rubin, S., … Graff, J. J. (2013). Social-cognitive processes associated with fear of recurrence among women newly diagnosed with gynecological cancers. Gynecologic Oncology, 128(1), 120–127.Google Scholar
- Phipps, S., & Mulhern, R. K. (1995). Family cohesion and expressiveness promote resilience to the stress of pediatric bone marrow transplant: A preliminary report. Journal of Developmental and Behavioral Pediatric, 16(4), 257–263.Google Scholar
- Pistrang, N., & Barker, C. (1995). The partner relationship in psychological response to breast cancer. Social Science and Medicine, 40(6), 789–797.Google Scholar
- Porter, L. S., Keefe, F. J., Wellington, C., & de Williams, A. (2008). Pain communication in the context of osteoarthritis: Patient and partner self-efficacy for pain communication and holding back from discussion of pain and arthritis-related concerns. Clinical Journal of Pain, 24(8), 662–668.PubMedCrossRefGoogle Scholar
- Rini, C., Manne, S., DuHamel, K. N., Austin, J., Ostroff, J., Boulad, F., … Redd, W. H. (2008). Social support from family and friends as a buffer of low spousal support among mothers of critically ill children: A multilevel modeling approach. Health Psychology, 27(5), 593–603.Google Scholar
- Titman, P., Pink, E., Skucek, E., O’Hanlon, K., Cole, T. J., Gaspar, J., … Gaspar, H. B. (2008). Cognitive and behavioral abnormalities in children after hematopoietic stem cell transplantation for severe congenital immunodeficiencies. Blood, 112(9), 3907–3913.Google Scholar
- Wong, M. G., & Heriot, S. A. (2008). Parents of children with cystic fibrosis: How they hope, cope, and despair. Child: Care, Health, and Development, 34, 344–354.Google Scholar
- Zhou, E. S., Penedo, F. J., Bustillo, N. E., Benedict, C., Rasheed, M., Lechner, S., … Antoni, M. H. (2010). Longitudinal effects of social support and adaptive coping on the emotional well-being of survivors of localized prostate cancer. The Journal of Supportive Oncology, 8(5), 196–201.Google Scholar