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Validation of the new Complior sensor to record pressure signals non-invasively

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Abstract

The Complior device (Alam Medical, France) has contributed to the rise of arterial stiffness as a measure of cardiovascular risk. In its latest version (Complior Analyse) the sensor records pressure instead of distension waveforms thus allowing the measurement of central pressure and pulse wave analysis. The aim of our study was to verify that the new sensor measures pressure waveforms accurately in both time and frequency domain. Invasive and non-invasive signals were recorded simultaneously at the radial artery and compared in the frequency and time domain in haemodynamically stable intensive care unit patients. Twelve patients entered the study (8 men, 4 women, mean age 69 ± 17 years). Heart rate was 90 ± 15 bpm, systolic blood pressure 133 ± 19 mmHg and diastolic blood pressure 68 ± 15 mmHg. There was no statistical difference in the amplitude of harmonics between the invasive signal and Complior signal. When superimposing waveforms in the time domain, there was a small difference in the form factor (4.2 ± 2.8 %) and in the absolute area between the 2 waveforms (3.3 ± 1.7 mmHg·s−1). These differences were of the same magnitude as the beat-to-beat variation of the form factor (3.3 %) and of the absolute area (3.1 mmHg·s−1), respectively. The second systolic peak was detectable in 4 subjects, with no statistical difference between invasive and non-invasive values. The new pressure sensor of the Complior Analyse device recorded pressure waveforms accurately and could be used to perform pressure wave analysis.

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Conflict of interest

Sandrine Millasseau works as a freelance specialist on pulse wave analysis and receives revenues from several medical companies including AtCor, Omron (both cited in this article) and Alam Medical whose sensors have been validated in this study. The other authors have no conflict of interest to declare in the subject matter. Alam Medical freely loaned a Complior Analyse device for the duration of the study.

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Authors and Affiliations

  1. Réanimation Médicale, Hôpital Antoine Béclère, Université Paris Sud, Assistance Publique-Hôpitaux de Paris, Paris, France

    Benjamin Sztrymf, Frédéric Jacobs & Christian Richard

  2. EA4533-Faculté de Médecine Paris Sud 11, Réanimation médicale, CHU Bicêtre, Paris, France

    Denis Chemla & Christian Richard

  3. Pulse Wave Consulting, 72b rue de Montlignon, 95320, Saint Leu la Foret, France

    Sandrine C. Millasseau

Authors
  1. Benjamin Sztrymf
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  2. Frédéric Jacobs
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  3. Denis Chemla
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  4. Christian Richard
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  5. Sandrine C. Millasseau
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Correspondence to Sandrine C. Millasseau.

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Sztrymf, B., Jacobs, F., Chemla, D. et al. Validation of the new Complior sensor to record pressure signals non-invasively. J Clin Monit Comput 27, 613–619 (2013). https://doi.org/10.1007/s10877-013-9477-y

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  • DOI: https://doi.org/10.1007/s10877-013-9477-y

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