Skip to main content
SpringerLink
Log in

Facile Green Synthesis of SnO2 NPs Using Vitex altissima (L.) Leaves Extracts: Characterization and Evaluation of Antibacterial and Anticancer Properties

  • Original Paper
  • Published:
Journal of Cluster Science Aims and scope Submit manuscript

Abstract

An eco-friendly approach is introduced for the synthesis of SnO2 nanoparticles using the Vitex altissima L. plant extract. Bioinspired mediated synthesis of nanoparticles have been suggested as a very simple, inexpensive, non-toxic and environmental manner. The presence of biomolecules in V. altissima induced the metal salts to form metal oxides. The prepared SnO2 NPs were characterized by XRD, UV–Vis, FT-IR, SEM and TEM Techniques. The PXRD patterns revealed that SnO2 nanoparticles exhibits tetragonal structure and its average crystallite size of SnO2 NPs is found in the range of ~ 10 to 20 nm. The UV–visible absorption spectrum of SnO2 nanoparticles showed absorption band at 257 nm and its band gap was found to be 4.18 eV. FTIR spectrum of green synthesized SnO2 NPs shows the band at 534.22 cm−1 which indicates O–Sn–O stretching vibration modes. The morphological features of SnO2 nanoparticles were fundamentally dependent up on concentration of V. altissima leaves extract. Green synthesized SnO2 nanoparticles exhibit significant antibacterial activity against pathogenic bacterial strains by agar well diffusion method. Furthermore, the SnO2 NPs shows significant cytotoxic effect on MCF-7 cancerous cell line. This result indicates that, V. altissima leaves extract acts as a reducing agent for the formations of SnO2 NPs with effective biological properties.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6

Similar content being viewed by others

References

  1. G. Madhumitha and S. M. Roopan (2013). J. Nanomater. 951858, 1–12.

    Article  CAS  Google Scholar 

  2. R. Kumar, S. M. Roopan, A. Prabhakaran, V. G. Khanna, and S. Chakraborty (2012). Spectrochim. Acta Part A Mol. Biomol. Spectrosc. 90, 173–176.

    Article  CAS  Google Scholar 

  3. S. Harikrishnan and S. Kalaiselvam (2012). Thermochim. Acta 533, 46–55.

    Article  CAS  Google Scholar 

  4. F. Du, Z. Guo, and G. Li (2005). Mater. Lett. 59, 2563.

    Article  CAS  Google Scholar 

  5. S. Fujihara, T. Maeda, H. Ohgi, E. Hosono, H. Imai, and S.H. Kim (2004). Langmuir 20, 6476–6481.

    Article  CAS  PubMed  Google Scholar 

  6. Y. Liu, E. Koep, and M. Liu (2005). Chem. Mater. 17, 3997–4000.

    Article  CAS  Google Scholar 

  7. Z. R. Dai, J. L. Gole, J. D. Stout, and Z. L. Wang (2002). J. Phys. Chem. B 106, 1274–1279.

    Article  CAS  Google Scholar 

  8. J. Q. Hu, X. L. Ma, N. G. Shang, Z. Y. Xie, N. B. Wong, C. S. Lee, and S. T. Lee (2002). J. Phys. Chem. B 106, 3823–3826.

    Article  CAS  Google Scholar 

  9. F. Pourfayaz, A. Khodadadi, Y. Mortazavi, and S. S. Mohajerzadeh (2005). Sens. Actuators B 108, 172–176.

    Article  CAS  Google Scholar 

  10. G. Rajkumar, A. A. Rahuman, S. M. Roopan, V. G. Khanna, G. Elango, C. Kamaraj, A. A. Zahir, and K. Velayutham (2012). Spectrochim. Acta Part A Mol. Biomol. Spectrosc. 91, 23–29.

    Article  CAS  Google Scholar 

  11. S. M. Roopan, R. G. Madhumitha, A. A. Rahuman, C. Kamaraj, A. Bharathi, and T. V. Surendra (2013). Ind. Crop. Prod. 43, 631–635.

    Article  CAS  Google Scholar 

  12. J. Pal and P. Chauhan (2009). Mater. Charact. 60, 1512–1516.

    Article  CAS  Google Scholar 

  13. J. Malleshappa, H. Nagabhushana, S. C. Prashantha, S. C. Sharma, N. Dhananjaya, C. Shivakumara, and B. M. Nagabhushana (2014). J. Alloys Compd. 612, 425–434.

    Article  CAS  Google Scholar 

  14. C. Sridhar, K. V. Rao, and G. V. Subbaraju (2005). Phytochemistry 66, 1707–1712.

    Article  CAS  PubMed  Google Scholar 

  15. D. Suresh, N. Udayabhanu, P. C. Nethravathi, K. Lingaraju, H. Rajanaika, S. C. Sharma, and H. Nagabhushana (2015). Spectrochim. Acta Part A Mol. Biomol. Spectrosc. 136, 1467–1474.

    Article  CAS  Google Scholar 

  16. A. K. Ramasami, H. Rajanaika, H. Nagabhushana, T. Ramakrishnappa, G. R. Balakrishna, and G. Nagaraju (2015). Mater. Charact. 99, 266–276.

    Article  CAS  Google Scholar 

  17. G. Elango, S. Manoj Kumaran, S. Santhosh Kumar, S. Muthuraja, and S. M. Roopan (2015). Spectrochim. Acta Part A Mol. Biomol. Spectrosc. 145, 176–180.

    Article  CAS  Google Scholar 

  18. K. Manjunath, T. N. Ravishankar, D. Kumar, K. P. Priyanka, T. Varghese, H. Rajanaika, H. Nagabhushana, S. C. Sharma, J. Dupont, T. Ramakrishnappa, and G. Nagaraju (2014). Mater. Res. Bull. 57, 325–334.

    Article  CAS  Google Scholar 

  19. H. Rajanaika and V. Krishna (2006). Int. J. Biomed. Pharm. Sci. 1, 69–72.

    Google Scholar 

  20. K. Lingaraju, H. Rajanaika, K. Manjunath, G. Nagaraju, D. Suresh, and H. Nagabhushana (2015). Acta Metall. Sin. 28, 1134–1140.

    Article  CAS  Google Scholar 

  21. H. Rajanaika, K. Lingaraju, K. Manjunath, D. Kumar, G. Nagaraju, D. Suresh, and H. Nagabhushana (2015). J. Taibah Univ. Sci. 9, 7–12.

    Article  Google Scholar 

  22. H. R. Prakash Naik, H. S. Bhojya Naik, T. R. Ravikumar Naik, H. Rajanaika, K. Gouthamchandra, R. Mahmood, and B. M. Khadeer Ahamed (2009). Eur. J. Med. Chem. 44, 981–989.

    Article  CAS  Google Scholar 

  23. J. Wang, X. X. Du, H. Jiang, and J. X. Xie (2009). Biochem. Pharmacol. 78, 178–183.

    Article  CAS  PubMed  Google Scholar 

  24. H. Nagabhushana, D. V. Sunitha, S. C. Sharma, B. D. Prasad, B. M. Nagabhushana, and R. P. S. Chakradhar (2014). J. Alloys Compd. 575, 192–199.

    Article  CAS  Google Scholar 

  25. J. Malleshappa, H. Nagabhushana, S. C. Sharma, Y. S. Vidya, K. S. Anantharaju, S. C. Prashantha, B. Daruka Prasad, H. Rajanaika, K. Lingaraju, and B. S. Surendra (2015). Spectrochim. Acta Part A Mol. Biomol. Spectrosc. 149, 452–462.

    Article  CAS  Google Scholar 

  26. H. B. Premkumar, H. Nagabhushana, S. C. Sharma, S. C. Prashantha, H. P. Nagaswarupa, B. M. Nagabhushana, and R. P. S. Chakradhar (2014). J. Alloys Compd. 601, 75–84.

    Article  CAS  Google Scholar 

  27. R. Bhatt, I. Bhaumik, S. Ganesamoorthy, A. K. Karnal, M. K. Swami, H. S. Patel, and P. K. Gupta (2012). Phys. Stat. Solid A 209, 176–180.

    Article  CAS  Google Scholar 

  28. Y. Liu, F. Yang, and X. Yang (2008). Colloid Surf. A 312, 219–225.

    Article  CAS  Google Scholar 

  29. N. Srivastava and M. Mukhopadhyay (2014). Ind. Eng. Chem. Res. 53, 13971–13979.

    Article  CAS  Google Scholar 

  30. S. Makhluf, R. Dror, Y. Nitzan, Y. Abramovich, R. Jelinek, and A. Gedanken (2005). Adv. Func. Mater. 15, 1708–1715.

    Article  CAS  Google Scholar 

  31. L. Zhang, Y. Jiang, Y. Ding, M. Povey, and D. York (2007). J. Nano. Res. 9, 479–489.

    Article  CAS  Google Scholar 

  32. M. I. Sriram, S. B. Kanth, K. Kalishwaralal, and S. Gurunathan (2010). Int. J. Nano Med. 5, 753–762.

    CAS  Google Scholar 

Download references

Acknowledgements

The authors are grateful to the UGC-RGNF, New Delhi, Government of India for financial assistance and also thanks for Tumkur University, proving the laboratories for research works are gratefully acknowledged.

Author information

Authors and Affiliations

  1. Department of Studies and Research in Biochemistry, Tumkur University, Tumakuru, India

    S. Bhavana, Vinod Gubbiveeranna, C. G. Kusuma, C. K. Sumachirayu & S. Nagaraju

  2. Department of Life Science, Jnana Bharthi Campus, Bangalore University, Bangalore, India

    H. Ravikumar

  3. Department of Studies and Research in Physics, Prof. C.N.R. Rao Block, Tumkur University, Tumakuru, India

    H. Nagabhushana

Authors
  1. S. Bhavana
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Vinod Gubbiveeranna
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. C. G. Kusuma
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. H. Ravikumar
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. C. K. Sumachirayu
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. H. Nagabhushana
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. S. Nagaraju
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to S. Nagaraju.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Bhavana, S., Gubbiveeranna, V., Kusuma, C.G. et al. Facile Green Synthesis of SnO2 NPs Using Vitex altissima (L.) Leaves Extracts: Characterization and Evaluation of Antibacterial and Anticancer Properties. J Clust Sci 30, 431–437 (2019). https://doi.org/10.1007/s10876-019-01496-w

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10876-019-01496-w

Keywords

Search

Navigation