Abstract
By combining the advantages of manganese dioxide nanoparticles (MnO2 NPs) and carbon nanofibers (CNFs), a biosensing electrode surface as a high-performance enzyme biosensor is designed in this work. MnO2 NPs and CNFs nanocomposites (MnO2–CNFs) were prepared by using a simple hydrothermal method and then were characterized by scanning electron microscopy, powder X-ray diffraction, fourier transform infrared spectroscopy, energy dispersive spectrometry and electrochemisty. The results showed that MnO2 NPs are uniformly attached to the surface of CNFs. Meanwhile, the MnO2–CNFs nanocomposites as a supporting matrix can provide an efficient and advantageous platform for electrochemical sensing applications. On the basis of the improved sensitivity of MnO2–CNFs modified electrode toward H2O2 at low overpotential, a MnO2–CNFs based glucose biosensor was fabricated by monitoring H2O2 produced by an enzymatic reaction between glucose oxidase and glucose. The constructed biosensor exhibited a linear calibration graph for glucose in a concentration range of 0.08–4.6 mM and a low detection limit of 0.015 mM. In addition, the biosensor showed other excellent characteristics, such as high sensitivity and selectivity, short response time, and the relative low apparent Michaelis–Menten constant. Analysis of human urine spiked with glucose at different concentration levels yielded recoveries between 101.0 and 104.8%.
Similar content being viewed by others
References
Y. Liu, M. K. Wang, F. Zhao, Z. A. Xu, and S. J. Dong (2005). Biosens. Bioelectron. 21, 984.
A. Chalupniak, A. Merkoci, and A. C. S. Appl (2017). Mater. Interfaces 9, 44766.
V. Vamvakaki, K. Tsagaraki, and N. Chaniotakis (2006). Anal. Chem. 78, 5538.
L. Wu, X. J. Zhang, and H. X. Ju (2007). Anal. Chem. 79, 453.
C. Shan, H. Yang, J. Song, D. Han, A. Ivaska, and L. Niu (2009). Anal. Chem. 81, 2378.
W. Song, D. W. Li, Y. T. Li, Y. Li, and Y. T. Long (2011). Biosens. Bioelectron. 26, 3181.
A. Arvinte, F. Valentini, A. Radoi, F. Arduini, E. Tamburri, L. Rotariu, G. Palleschi, and C. Bala (2007). Electroanalysis 19, 1455.
Y. Liu, H. Q. Hou, and T. Y. You (2008). Elactroanalysis 20, 1708.
L. Wu, X. J. Zhang, and H. X. Ju (2007). Analyst 132, 406.
V. Vamvakaki and N. A. Chaniotakis (2007). Sens. Actuators B 126, 193.
Z. Z. Li, X. L. Cui, J. S. Zheng, Q. F. Wang, and Y. H. Lin (2007). Anal. Chim. Acta 597, 238.
Y. Liu, J. S. Huang, H. Q. Hou, and T. Y. You (2008). Electrochem. Commun. 10, 1431.
L. Wu, X. J. Zhang, and H. X. Ju (2007). Biosens. Bioelectron. 23, 479.
X. B. Lu, J. H. Zhou, W. Lu, Q. Liu, and J. H. Li (2008). Biosens. Bioelectron. 23, 1236.
C. Hao, L. Ding, X. J. Zhang, and H. X. Ju (2007). Anal. Chem. 79, 4442.
J. S. Huang, D. W. Wang, H. Q. Hou, and T. Y. You (2008). Adv. Funct. Mater. 18, 441.
V. Vamvakaki, M. Hatzimarinaki, and N. A. Chaniotakis (2008). Anal. Chem. 80, 5970.
Q. Guo, D. Liu, X. Zhang, L. Li, H. Hou, O. Niwa, and T. Y. You (2014). Anal. Chem. 86, 5898.
V. E. Henrich and P. A. Cox, Cambridge University Press: Cambridge, UK, 1994.
S. J. Yao, S. Yuan, and J. H. Xu (2006). Y. wang, J. L. Luo and S. S. Hu. Appl. Clay Sci. 33, 35.
Y. H. Lin, X. L. Cui, and L. L. Yu (2005). Electrochem. Commun. 7, 166.
A. J. Wang, P. P. Zhang, Y. F. Li, J. J. Feng, W. J. Dong, and X. Y. Liu (2011). Microchim. Acta 175, 31.
Y. H. Bai, Y. Du, J. J. Xu, and H. Y. Chen (2007). Electrochem. Commun. 9, 2611.
L. Han, C. Shao, B. Liang, A. Liu, and A. C. S. Appl (2016). Mater. Interfaces 8, 13768.
E. A. Dontsova, Y. S. Zeifman, I. A. Budashov, A. V. Eremenko, S. L. Kalnov, and I. N. Kurochkin (2011). Sens. Actuators B Chem. 159, 261.
B. Xu, M. L. Ye, Y. X. Yu, and W. D. Zhang (2010). Anal. Chim. Acta 674, 20.
Y. Li, J. Zhang, H. Zhu, F. Yang, and X. Yang (2010). Electrochim. Acta 55, 5123.
A. J. Paleo, P. Staiti, A. Brigandì, F. N. Ferreira, A. M. Rocha, and F. Lufrano (2018). Energy Storage Mater. 12, 204.
Y. Yang, S. Lee, D. E. Brown, H. Zhao, X. Li, D. Jiang, S. Hao, Y. Zhao, D. Cong, X. Zhang, and Y. Ren (2016). Electrochim. Acta 211, 524.
Z. Zeng, W. Zhang, Y. Liu, P. Lu, and J. Wei (2017). Electrochim. Acta 256, 232.
H. Yang, Y. Yan, Y. Liu, F. Zhang, R. Zhang, Y. Meng, M. Li, S. Xie, B. Tu, and D. Zhao (2004). J. Phys. Chem. B 108, 17320.
K. Gong, P. Yu, L. Su, S. Xiong, and L. Mao (1882). J. Phys. Chem. C 2007, 111.
F. Cheng, J. Zhao, W. Song, C. Li, H. Ma, J. Chen, and P. Shen (2006). Inorg. Chem. 45, 2038.
W. Tian, H. Yang, X. Fan, and X. Zhang (2011). J. Hazard. Mater. 188, 105.
M. Sun, B. Lan, T. Lin, G. Cheng, F. Ye, L. Yu, X. Cheng, and X. Zheng (2013). CrystEngComm 15, 7010.
M. Zhi, A. Manivannan, F. Meng F, N. Wu, J Power Sources, 2012, 208, 345.
S. Kubota, H. Nishikiori, N. Tanaka, M. Endo, and T. Fujii (2005). J. Phys. Chem. B 109, 23170.
Q. Bao, S. Bao, C. M. Li, X. Qi, C. Pan, J. Zang, Z. Lu, Y. Li, D. Y. Tang, S. Zhang, and K. Lian (2008). J. Phys. Chem. C 112, 3612.
S. Jana, S. Basu, S. Pande, and S. Kumar (2007). Ghosh and T. Pal. J. Phys. Chem. C 111, 16272.
J. Zhu, J. He, and A. C. S. Appl (2012). Mater. Interfaces 4, 1770.
M. V. Ananth, S. Pethkar, and K. Dakshinamurthi (1998). J. Power Sources 75, 278.
W. Zhang, Z. Zeng, and J. Wei (2017). J. Phys. Chem. C 121, 18635.
Z. Zeng, Y. Liu, W. Zhang, H. Chevva, and J. Wei (2017). J. Power Sources 358, 22.
Y. F. Tang, B. L. Allen, D. R. Kauffman, and A. Star (2009). J. Am. Chem. Soc. 131, 13200.
S. B. Hocevar and B. Ogorevc (2004). K. Schachl amd K. Kalcher. Electroanalysis 16, 1711.
X. Xu, S. Jiang, Z. Hu, and S. Liu (2010). ACS Nano 4, 4292.
L. Zhang, S. Yuan, L. Yang, Z. Fang, and G. Zhao (2013). Microchim. Acta 180, 627.
R. A. Kamin and G. S. Wilson (1980). Anal. Chem. 52, 1198.
G. B. Xu, X. Q. Liu, L. H. Shi, W. X. Niu, and H. J. Li (1887). Biosens. Bioelectron. 2008, 23.
T. H. Wang, C. C. Li, Y. L. Liu, L. M. Li, Z. F. Du, S. J. Xu, M. Zhang, and X. M. Yin (2008). Talanta 77, 455.
B. A. Gregg and A. Heller (1990). Anal. Chem. 62, 258.
B. Akkaya, B. Çakiroğlu, and M. Özacar (2018). ACS Sustain. Chem. Eng. 6, 3805.
Acknowledgements
The authors thank the National Natural Science Foundation of China (21001004), the Natural Science Foundation of the Anhui Higher Education Institutions (Grant No. KJ2016A277), the Innovation Funds of Anhui Normal University (Grant 741606), Ph.D. Research Startup Funds of Anhui Normal University (2018XJJ-751862), the Key Laboratory of Functional Molecular Solids, Ministry of Education and Anhui Laboratory of Molecule-Based Materials (16005) and the Training Programs of Innovation and Entrepreneurship for Undergraduates (201610370471).
Author information
Authors and Affiliations
Corresponding author
Electronic supplementary material
Below is the link to the electronic supplementary material.
Rights and permissions
About this article
Cite this article
Zhang, L., Chen, Q., Han, X. et al. MnO2 Nanoparticles and Carbon Nanofibers Nanocomposites with High Sensing Performance Toward Glucose. J Clust Sci 29, 1089–1098 (2018). https://doi.org/10.1007/s10876-018-1421-3
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10876-018-1421-3