Journal of Cluster Science

, Volume 25, Issue 3, pp 839–854 | Cite as

Chitosan-Polyoxometalate Nanocomposites: Synthesis, Characterization and Application as Antimicrobial Agents

Original Paper


Polyoxometalates (POMs) were used, together with chitosan (CS), to obtain hybrid nanoaggregates. Three representative POMs were efficiently assembled into nanoparticles of few hundred nm diameter, featuring entangled ribbons substructure. In order to establish suitable preparation and stability conditions, the assemblies were characterized in solution by UV–Vis spectroscopy, dynamic light scattering and ζ-potential. The nanoparticles were tested against E. coli (106 CFU/ml) in aqueous solution, showing a synergic activity of the heteropolyacid H5PMo10V2O40 and CS. For such components, a highly porous and antibacterial film was obtained upon lyophilisation of the colloidal mixture.


Chitosan Polyoxometalates Nanoparticles Antimicrobial activity Porous film 



The research leading to these results has received funding from the European Union’s Seventh Framework Programme (FP7/2007–2013) under grant agreement n°246039 and from MIUR (FIRB prot. RBAP11ETKA). We would like to thank the Biotechnology and Bioengineering Application and Research Center staff at the Izmir Institute of Technology for their kind help and technical support. We also thank Dr. Claudio Furlan, CUGAS—University of Padova, for ESEM and EDAX analyses, and Dr. Federico Caicci, Biology Department, University of Padova, for TEM analysis.

Supplementary material

10876_2013_685_MOESM1_ESM.doc (8.5 mb)
Supplementary data associated with this article can be found in the online version: DLS and ζ-potential graphs, TEM, UV–Vis, FT-IR, ESEM and EDX analyses. (DOC 8729 kb)


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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.ITM-CNR and Department of Chemical SciencesUniversity of PadovaPaduaItaly
  2. 2.Department of Chemical EngineeringIzmir Institute of TechnologyUrlaTurkey
  3. 3.ITM-CNRRendeItaly

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