Skip to main content

Advertisement

SpringerLink
Log in

EBV-Related Hodgkin Lymphoma in an ICF2 Patient: Is EBV Susceptibility a Hallmark of This ICF Subtype?

  • Letter to Editor
  • Published:
Journal of Clinical Immunology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

References

  1. van den Boogaard ML, Thijssen PE, Aytekin C, Licciardi F, Kıykım AA, Spossito L, et al. Expanding the mutation spectrum in ICF syndrome: evidence for a gender bias in ICF2. Clin Genet. 2017;92:380–7.

    Article  CAS  PubMed  Google Scholar 

  2. Franceschini P et al. Variability of clinical and immunological phenotype in immunodeficiency-centromeric instability-facial anomalies syndrome. Report of two new.

  3. Sterlin D, Velasco G, Moshous D, Touzot F, Mahlaoui N, Fischer A, et al. Genetic, cellular and clinical features of ICF syndrome: a French National Survey. J Clin Immunol. 2016;36:149–59.

    Article  CAS  PubMed  Google Scholar 

  4. Harnisch E, Buddingh EP, Thijssen PE, Brooks AS, Driessen GJ, Kersseboom R, et al. Hematopoietic stem cell transplantation in a patient with ICF2 syndrome presenting with EBV-induced hemophagocytic lymphohystiocytosis. Transplantation. 2016;100:e35–6.

    Article  PubMed  Google Scholar 

  5. Kamae C et al. Clinical and immunological characterization of ICF syndrome in Japan. J Clin Immunol 2018; (ahead of print).

  6. Hernando H, Shannon-Lowe C, Islam AB, al-Shahrour F, Rodríguez-Ubreva J, Rodríguez-Cortez VC, et al. The B cell transcription program mediates hypomethylation and overexpression of key genes in Epstein-Barr virus-associated proliferative conversion. Genome Biol. 2013;14:R3.

    Article  PubMed  PubMed Central  Google Scholar 

  7. Velasco G, Grillo G, Touleimat N, Ferry L, Ivkovic I, Ribierre F, et al. Comparative methylome analysis of ICF patients identifies heterochromatin loci that require ZBTB24, CDCA7 and HELLS for their methylated state. Hum Mol Genet. 2018;27:2409–24.

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgments

We wish to thank Dr. Paola Campisi for providing the biopsy microscopical pictures.

Author information

Authors and Affiliations

  1. Division of Pediatric Immunology and Rheumatology, Department of Public Health and Pediatrics, “Regina Margherita” Children Hospital, University of Turin, P.zza Polonia 94, 10126, Turin, Italy

    Francesco Licciardi, Marta Delle Piane, Pier Angelo Tovo & Davide Montin

  2. Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands

    Marlinde van den Boogaard

Authors
  1. Francesco Licciardi
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Marlinde van den Boogaard
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Marta Delle Piane
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Pier Angelo Tovo
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Davide Montin
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Francesco Licciardi.

Ethics declarations

Conflict of Interest

The authors declare that they have no conflict of interest.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Licciardi, F., van den Boogaard, M., Delle Piane, M. et al. EBV-Related Hodgkin Lymphoma in an ICF2 Patient: Is EBV Susceptibility a Hallmark of This ICF Subtype?. J Clin Immunol 39, 234–236 (2019). https://doi.org/10.1007/s10875-019-00596-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10875-019-00596-6

Search

Navigation