Skip to main content

Advertisement

Log in

Successful Treatment with SCIG of a Child with Refractory Chronic ITP

  • Letter to Editor
  • Published:
Journal of Clinical Immunology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

References

  1. Kuhne T. Diagnosis and management of immune thrombocytopenia in childhood. Hamostaseologie. 2017;37(1):36–44.

    Article  PubMed  Google Scholar 

  2. Seidel MG. Autoimmune and other cytopenias in primary immunodeficiencies: pathomechanisms, novel differential diagnoses, and treatment. Blood. 2014;124(15):2337–44.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Ballow M. The IgG molecule as a biological immune response modifier: mechanisms of action of intravenous immune serum globulin in autoimmune and inflammatory disorders. J Allergy Clin Immunol. 2011;127(2):315–23 quiz 24-5.

    Article  CAS  PubMed  Google Scholar 

  4. Iuliano F, Iuliano E, Luci M, Perricelli A, Pomillo A, Abruzzese E. Subcutaneous immunoglobulin (SCIG) in responders to intravenous therapy with chronic immune thrombocytopenia (ITP). Blood. 2014;124(21):5012.

    Google Scholar 

  5. Pedini V, Savore I, Danieli MG. Facilitated subcutaneous immunoglobulin (fSCIg) in autoimmune cytopenias associated with common variable immunodeficiency. Isr Med Assoc J. 2017;19(7):420–3.

    PubMed  Google Scholar 

  6. Scheuerlein P, Pietsch L, Camacho-Ordonez N, Reiser V, Patel S, Burns SO, et al. Is it safe to switch from intravenous immunoglobulin to subcutaneous immunoglobulin in patients with common variable immunodeficiency and autoimmune thrombocytopenia? Front Immunol. 2018;9:1656.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Chapdelaine H, Decaluwe H, Levasseur MC, De Deist F, Haddad E. Experience with subcutaneous immunoglobulin therapy in two pediatric cases of immune thrombocytopenia purpura. Allergy, Asthma Clin Immunol. 2012;8(Suppl 1):A23.

    Article  Google Scholar 

  8. Cuker A, Neunert CE. How I treat refractory immune thrombocytopenia. Blood. 2016;128(12):1547–54.

    Article  CAS  PubMed  Google Scholar 

  9. DiMaggio D, Anderson A, Bussel JB. Cytomegalovirus can make immune thrombocytopenic purpura refractory. Br J Haematol. 2009;146(1):104–12.

    Article  PubMed  Google Scholar 

Download references

Acknowledgements

The authors thank the patient and her family for the approval to publish her clinical history and laboratory data. MGS is in part funded by the Styrian Children’s Cancer foundation (Steirische Kinderkrebshilfe).

Author information

Authors and Affiliations

Authors

Contributions

AK and MGS designed the study. AK, DK, HL, MB, and MGS cared for the patient and collected data. AK and DK analyzed the data. MM gave relevant advice in patient care and the discussion of the data. DK drafted the manuscript and the figures.

Corresponding authors

Correspondence to Anna Karastaneva or Daniela S. Klobassa.

Ethics declarations

Ethics Statement

Written informed consent was obtained from the participant’s next of kin for the publication of this patient report, which was conducted according to the Declaration of Helsinki.

Conflict of Interest

The authors declared that they have no conflict of interest.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Karastaneva, A., Klobassa, D.S., Minkov, M. et al. Successful Treatment with SCIG of a Child with Refractory Chronic ITP. J Clin Immunol 39, 19–22 (2019). https://doi.org/10.1007/s10875-018-0583-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10875-018-0583-y

Navigation