Journal of Clinical Immunology

, Volume 36, Issue 1, pp 66–72 | Cite as

Magnetic Resonance Imaging May Be a Valuable Radiation-Free Technique for Lung Pathologies in Patients with Primary Immunodeficiency

  • Sevket Arslan
  • Necdet Poyraz
  • Ramazan Ucar
  • Mihrican Yesildag
  • Ahmet Yesildag
  • Ahmet Zafer Caliskaner
Original Article



In some primary immunodeficiency (PID) patients, especially in the subgroup with common variable immunodeficiency (CVID), radiosensitivity is a concern and avoidance of repeated radiation exposure has been recommended. To investigate the use of lung Magnetic resonance imaging (MRI) instead of Computed Tomography (CT) for the diagnosis and follow-up of various lesions in the lung parenchyma and airways, especially in PID patients in whom x-ray exposure should be limited.


The study enrolled 23 patients with PID who underwent thorax CT within the last 3 months and/or who will undergo initial radiological assessment. Lung MRI was performed in all patients to compare the pulmonary findings with CT images.


MRI performance was weaker at detecting bronchiectasis extension, and a low concordance was found between MRI and CT in the assessment of the number of bronchial generations. CT better identified peripheral airway abnormalities, while CT and MRI gave similar results for detecting the presence and extension of consolidation, bullae, mucus plugging, bronchial wall thickening, bronchiectasis severity and nodules.


Despite the low spatial resolution, higher cost, and low availability, we suggest MRI as a possible radiation-free alternative to CT in selected patients with PID.


Primary immunodeficiency radiosensitivity lung imaging computerized tomography magnetic resonance imaging 


Compliance with ethical standards

Financial Disclosure

There is no financial disclosure.

Conflict of Interest

The authors have no conflicts of interest.


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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • Sevket Arslan
    • 1
  • Necdet Poyraz
    • 2
  • Ramazan Ucar
    • 1
  • Mihrican Yesildag
    • 3
  • Ahmet Yesildag
    • 2
  • Ahmet Zafer Caliskaner
    • 1
  1. 1.Faculty of Medicine, Department of Internal Medicine, Division of Allergy and Immunology DiseasesNecmettin Erbakan University MeramKonyaTurkey
  2. 2.Faculty of Medicine, Department of RadiologyNecmettin Erbakan University MeramKonyaTurkey
  3. 3.Department of Chest DiseasesKonya Training and Research HospitalKonyaTurkey

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