Journal of Chemical Crystallography

, Volume 44, Issue 7, pp 380–385 | Cite as

Breaking Down the Interdigitated Dimeric Structure of Calix[4]arenediphosphonic Acid: the Structures of the Complexes with Piroxicam and 9-Aminoacridine

  • Aleksander Shkurenko
  • Hassim Seriouna
  • Karim Kedim
  • Jean-Baptiste Gervès
  • Kinga Suwinska
  • Anthony W. Coleman
Original Paper


The solid-state structures of the complexes of calix[4]arenediphosphonic acid with piroxicam and 9-aminoacridine are described, in both cases, the classical interdigitated dimer formed by calix[4]arenediphosphonic acid is no longer present. For the 9-aminoacridine complex, a π–π stacked dimer of 9-aminoacridine is surrounded by calix[4]arenediphosphonic acid molecules with dimethyl sulfoxide included in the calix arene cavity. In the case of the piroxicam complex the piroxicam molecule forms a true inclusion complex and the pyridinium ring projects out to hydrogen bond to an opposing calix[4]arenediphosphonic acid, thus spanning the bilayer.

Graphical Abstract

The structures of the complexes of calix[4]arenediphosphonic acid with piroxicam and 9-aminoacridine show a breakdown in the classical interdigated calix-arene dimer with formation of trus inclusion complexes and exo-complexation.


Co-crystal Calix[4]arenediphosphonic acid Piroxicam 9-Aminoacridine Layer structure 

Supplementary material

10870_2014_526_MOESM1_ESM.doc (84 kb)
Supplementary material 1 (DOC 83 kb)


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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • Aleksander Shkurenko
    • 1
  • Hassim Seriouna
    • 2
  • Karim Kedim
    • 2
  • Jean-Baptiste Gervès
    • 2
  • Kinga Suwinska
    • 1
    • 3
  • Anthony W. Coleman
    • 2
  1. 1.Institute of Physical Chemistry, Polish Academy of SciencesWarsawPoland
  2. 2.LMI, Université Lyon 1 CNRS UMR 5615VilleurbanneFrance
  3. 3.Faculty of Biology and Environmental SciencesCardinal Stefan Wyszynski UniversityWarsawPoland

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