Journal of Chemical Crystallography

, Volume 41, Issue 8, pp 1158–1164 | Cite as

Synthesis and Crystal Structure of New Heterocyclic Compounds Containing 1,2,3-Triazole Moiety

Original Paper


A series of new heterocyclic compounds bearing 1,2,3-triazole moiety were synthesized using 4-acetyl-2-phenyl-1,2,3-triazole 1 as the starting material. The target compounds were prepared and the structures were characterized by IR, 1H NMR, MS and elemental analysis. Meanwhile, the crystal structures of the synthesized compounds were also furthered confirmed by X-ray diffraction analysis. Compound 3b crystallized in the monoclinic P2(1)/c space group with unit cell parameters a = 10.6974(17) Å, b = 20.356(3) Å, c = 7.8049(12) Å, α = 90°, β = 102.840(3)°, γ = 90º, V = 1657.1(5) Å3, Z = 4, T = 293(2) K. Compound 7c crystallized in the Triclinic P-1 space group with unit cell parameters a = 7.364(2) Å, b = 7.366(2) Å, c = 26.089(8)Å, α = 87.114(7)°, β = 87.040(7) (3)°, γ = 82.337(7)°, V = 1399.2(7) Å3, Z = 2, T = 293(2) K. Compound 10c crystallized in the Triclinic P-1 space group with unit cell parameters a = 9.8152(10) Å, b = 10.0806(13) Å, c = 11.1267(14) Å, α = 100.344(3)°, β = 111.975(3)°, γ = 107.852(3)°, V = 916.18(19) Å3, Z = 2, T = 293(2) K.

Graphical Abstract

New heterocyclic compounds bearing 1,2,3-triazole moiety were synthesized, which may have potential biological and medical applications.


1,2,3-Triazole Isoxazole Thiadiazine Oxadiazoline 



This work was supported by the National Natural Science Foundation of China (Nos. 20562011, 20662009).


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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Zhi-Qiang Dong
    • 1
  • Fang-Ming Liu
    • 1
    • 2
  • Yong-Ming Zeng
    • 2
  1. 1.College of Materials and Chemical EngineeringHangzhou Normal UniversityHangzhouPeople’s Republic of China
  2. 2.College of Chemistry and Chemical EngineeringXinjiang UniversityUrumqiPeople’s Republic of China

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