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Journal of Chemical Crystallography

, Volume 41, Issue 6, pp 895–897 | Cite as

Crystal Structure of (1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-4-(oxo-\κO)-3-quinolinecarboxylato-κO3) difluoro-boron

  • Derek A. Beauchamp
  • Xun Li
  • Ronald K. Russell
Communication
  • 63 Downloads

Abstract

The complex (1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-4-(oxo-\κO)-3-quinolinecarboxylato-κO3) difluoro-boron crystallizes in the monoclinic space group P21/c, a = 11.43400(10) Å, b = 9.16420(10) Å, c = 13.8745(2) Å, β = 106.6470(10)º, V = 1392.89(3) Å3, and Z = 4; which is a resonance hybrid with an almost tetrahedral boron which produces a 6-membered ring, where the boron atom is slightly bent out of plane.

Graphical Abstract

The manuscript shows and describes the crystal structure of the complex, (1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-4-(oxo-\κO)-3-quinolinecarboxylato-κO3) difluoro-boron.

Keywords

Crystal structure Difluoro-boron Resonance hybrid Fluoroquinilone 

Notes

Acknowledgments

The authors would like to thank Bruce Noll of Bruker AXS for assistance and discussion regarding the final refinement of the structure.

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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Derek A. Beauchamp
    • 1
  • Xun Li
    • 1
  • Ronald K. Russell
    • 1
  1. 1.Johnson and Johnson Pharmaceutical Research & Development, L.L.C.Spring HouseUSA

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