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Crystal Structure of (1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-4-(oxo-\κO)-3-quinolinecarboxylato-κO3) difluoro-boron

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Abstract

The complex (1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-4-(oxo-\κO)-3-quinolinecarboxylato-κO3) difluoro-boron crystallizes in the monoclinic space group P21/c, a = 11.43400(10) Å, b = 9.16420(10) Å, c = 13.8745(2) Å, β = 106.6470(10)º, V = 1392.89(3) Å3, and Z = 4; which is a resonance hybrid with an almost tetrahedral boron which produces a 6-membered ring, where the boron atom is slightly bent out of plane.

Graphical Abstract

The manuscript shows and describes the crystal structure of the complex, (1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-4-(oxo-\κO)-3-quinolinecarboxylato-κO3) difluoro-boron.

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Scheme 1
Fig. 1

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Acknowledgments

The authors would like to thank Bruce Noll of Bruker AXS for assistance and discussion regarding the final refinement of the structure.

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Authors and Affiliations

  1. Johnson and Johnson Pharmaceutical Research & Development, L.L.C., Welsh & McKean Roads, Spring House, PA, 19477, USA

    Derek A. Beauchamp, Xun Li & Ronald K. Russell

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  1. Derek A. Beauchamp
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  2. Xun Li
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  3. Ronald K. Russell
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Correspondence to Derek A. Beauchamp.

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Beauchamp, D.A., Li, X. & Russell, R.K. Crystal Structure of (1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-4-(oxo-\κO)-3-quinolinecarboxylato-κO3) difluoro-boron. J Chem Crystallogr 41, 895–897 (2011). https://doi.org/10.1007/s10870-011-0058-y

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