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Journal of Chemical Crystallography

, Volume 40, Issue 2, pp 116–121 | Cite as

Synthesis and Crystal Structures of o-[(Phenyl/p-methoxyphenyl)carbamoyl]benzene Sulfonamides

  • Waseeq Ahmad Siddiqui
  • Saeed Ahmad
  • Hamid Latif Siddiqui
  • Tanvir Hussain
  • Masood Parvez
ORIGINAL PAPER

Abstract

o-[(Phenyl/p-methoxyphenyl)carbamoyl]benzene sulfonamides were synthesized in a straightforward manner utilizing directly saccharin and aniline/p-anisidine as starting material and their crystal structures have been determined. (C13H12N2O3S): Mr = 276.31, monoclinic, P21/c, a = 10.277(6), b = 7.501(2), c = 16.261(10) Å, β = 96.37(2)°, V = 1,245.8(11) Å3, Z = 4. (C14 H14 N2 O4 S): Mr = 306.33, monoclinic, P21/c, a = 10.381(5), b = 7.861(2), c = 16.837(9) Å, β = 93.43(2)°, V = 1,371.5(10) Å3, Z = 4. In both structures the phenyl rings are inclined at 47.09(7) and 39.88(5)° with respect to each other and the structures are characterized by extensive inter and intramolecular hydrogen bonds.

Graphical Abstract

The synthesis and crystal structures of two novel [(aryl)carbamoyl]benzene sulfonamide derivatives have been presented.

Keywords

Sulfonamides o-[(Aryl)carbamoyl]benzene sulfonamides Biological activities Crystal structure 

Notes

Acknowledgments

The authors acknowledge the Higher Education Commission (HEC), Pakistan, for funding this research.

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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Waseeq Ahmad Siddiqui
    • 1
  • Saeed Ahmad
    • 2
  • Hamid Latif Siddiqui
    • 3
  • Tanvir Hussain
    • 3
  • Masood Parvez
    • 4
  1. 1.Department of ChemistryUniversity of SargodhaSargodhaPakistan
  2. 2.Department of ChemistryUniversity of Science and TechnologyBannuPakistan
  3. 3.Institute of ChemistryUniversity of the PunjabLahorePakistan
  4. 4.Department of ChemistryUniversity of CalgaryN.W. CalgaryCanada

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