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Journal of Chemical Crystallography

, Volume 39, Issue 7, pp 519–524 | Cite as

Spectroscopic Investigation on the Formation of a Dinuclear Me2SO–Ru2-Mercaptopyridine Bridged Complex: [Ru2Cl3(μ-pyS)(μ-dmso)(dmso)4] · 2H2O

  • Queite Antônia de Paula
  • Sauli dos SantosJr.
  • Javier Ellena
  • Eduardo E. Castellano
  • Alzir A. Batista
Original Paper

Abstract

A dinuclear ruthenium(II) complex double-bridged by an N-aromatic ligand 2-mercaptopyridine (2-pyridinethiol or 2-pyridyl mercaptan) and a methyl sulfoxide (dmso) have been characterized by X-ray crystallography. The reported compound with formula [Ru2Cl3(μ-pyS)(μ-dmso)(dmso)4] · 2H2O, [C15H36Cl3NO7S6Ru2] (P2/c, a = 13.8175(2) Å, b = 10.5608(2) Å, c = 21.3544(3) Å, β = 106.090(1)°, V = 2,994.05(8) Å3, Z = 4) represents a seven-membered ring system with both rutheniums in an octahedral geometry. All the hydrogen bonds (C–H–Cl) and the van der Waals contacts give rise to three-dimensional network in the structure and add stability to the dinuclear compound. To our knowledge, this is the first time that the formation of a dinuclear ruthenium(II) complex double-bridged by an N-aromatic ligand 2-mercaptopyridine and dmso have been reported. The study also provided valuable insight into bioinorganic chemistry as continuing efforts are being made to develop metal-based cancer chemotherapeutics. A major feature of this paper is the resolution of a double bridged ruthenium structure which contributes to a better understanding of ruthenium reactivity.

Index Abstract

A major feature of this paper is the resolution of a double bridged ruthenium structure which contributes to a better understanding of ruthenium reactivity.

Keywords

Ruthenium Cancer 2-Mercaptopyridine Binuclear compound 

Notes

Acknowledgments

The authors are grateful to the Brazilian financial agencies CNPq (Conselho Nacional de Pesquisa e Desenvolvimento), CAPES (Coordenação de Aperfeiçoamento de Pessoal de Nível Superior) and, FAPESP (Fundação de Amparo à Pesquisa do Estado de São Paulo). They kindly acknowledge K. Harding for the suggestions.

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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Queite Antônia de Paula
    • 1
    • 3
  • Sauli dos SantosJr.
    • 2
  • Javier Ellena
    • 2
  • Eduardo E. Castellano
    • 2
  • Alzir A. Batista
    • 1
  1. 1.Departamento de QuímicaUniversidade Federal de São CarlosSão CarlosBrazil
  2. 2.Instituto de Física de São CarlosUniversidade de São PauloSão CarlosBrazil
  3. 3.Department of ChemistryVirginia Commonwealth UniversityRichmondUSA

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