Journal of Behavioral Medicine

, Volume 28, Issue 1, pp 105–114 | Cite as

Initiation and Discontinuation of Hormone Therapy for Menopausal Symptoms: Results From a Community Sample

  • Hayden B. Bosworth
  • Lori A. Bastian
  • Steven C. Grambow
  • Colleen M. McBride
  • Celette Sugg Skinner
  • Laura Fish
  • Barbara K. Rimer
  • Ilene C. Siegler


Factors related to initiation and discontinuation of hormonal therapy (HT) for treatment of menopausal symptoms were examined in a community sample of 533 peri/postmenopausal women aged 45–54 by telephone three times. Over 40 variables including: sociodemographic characteristics, clinical reasons to start HT use, HT contraindications, HT attitudes/knowledge, and health behaviors were examined in logistic regression models comparing women who discontinued HT to women who continued using HT over 9 months (discontinuers) and women who initiated HT versus women who never used HT over 9 months (initiators). Increased understanding of HT, confidence, mental health symptoms, perception that menopause is natural, and having gynecological surgery were related to decreased likelihood of HT discontinuation. Increased understanding about risks of HT, vasomotor symptoms, mood symptoms, and having gynecological surgery were related to increased likelihood of HT Initiation. These findings highlight the importance of physicians discussing HT with their patients, particularly because of recent clinical trial developments.


menopause hormonal replacement medication patient–physician communication adherence climacteric symptoms 


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Copyright information

© Springer Science + Business Media, Inc. 2005

Authors and Affiliations

  • Hayden B. Bosworth
    • 1
    • 2
    • 3
    • 4
  • Lori A. Bastian
    • 1
    • 2
    • 4
  • Steven C. Grambow
    • 1
    • 5
  • Colleen M. McBride
    • 6
    • 7
  • Celette Sugg Skinner
    • 6
    • 7
  • Laura Fish
    • 6
  • Barbara K. Rimer
    • 8
  • Ilene C. Siegler
    • 3
    • 4
    • 6
  1. 1.Center for Health Services Research in Primary CareDurham VAMCDurham
  2. 2.Department of Medicine, Division of General Internal MedicineDuke University Medical CenterDurham
  3. 3.Department of Psychiatry and Behavioral SciencesDuke University Medical CenterDurham
  4. 4.Center for Aging and Human DevelopmentDuke UniversityDurham
  5. 5.Department of Biostatistics and BioinformaticsDuke University Medical CenterDurham
  6. 6.Cancer Prevention, Detection, and Control Research ProgramDuke Comprehensive Cancer CenterDurham
  7. 7.Department of Community and Family MedicineDuke University Medical CenterDurham
  8. 8.8Department of Health Behavior and Health Education, School of Public HealthUniversity of North Carolina at Chapel HillChapel Hill

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