Fabrication of hydroxyapatite on pure titanium by micro-arc oxidation coupled with microwave-hydrothermal treatment

  • Quan-ming Zhao
  • Hui-lin Yang
  • Zhong-tang Liu
  • Xiao-feng Gu
  • Cheng Li
  • De-hong Feng
Engineering and Nano-engineering Approaches for Medical Devices
Part of the following topical collections:
  1. Engineering and Nano-engineering Approaches for Medical Devices


Porous hydroxyapatite (HA)-containing composite films were prepared by a novel method consisting of micro-arc oxidation (MAO) combined with microwave-hydrothermal (M-H) treatment. The morphology, composition and phase composition of the bioactive films were investigated with scanning electron microscopy with energy dispersive X-ray spectroscopy and X-ray diffraction. MTT assay was carried out to investigate the in vitro effects of the different surfaces on bone integration properties. The prepared MAO films consisted mainly of anatase, rutile and tricalcium phosphate along with amorphous calcium (Ca) and phosphorus (P) phases. The M-H-treated composite films were composed primarily of anatase, rutile and HA. As the time and temperature of the M-H treatment increased, the number of HA crystals gradually increased. Using the M-H method, HA was obtained at a lower temperature and in a shorter period of time compared to the conventional hydrothermal method. The results suggest that the M-H method significantly decreases the hydrothermal reaction temperature and also greatly shortens the reaction time. Due to the nanocrystallinity and porosity of the prepared composite films, the method presented here shows promise for the formation of bioactive materials for medical applications.


Composite Film Plasma Electrolytic Oxidation Porous Titanium Bioactive Film Pure Titanium Substrate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



This work was supported by a Grant from the Natural Science Foundation of Jiangsu Province (BK20140123), National Nature Science Foundation of China (81171689, 81301559) and Jiangsu Provincial Special Program of Medical Science (BL2012004).


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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • Quan-ming Zhao
    • 1
  • Hui-lin Yang
    • 1
  • Zhong-tang Liu
    • 2
  • Xiao-feng Gu
    • 3
  • Cheng Li
    • 3
  • De-hong Feng
    • 3
  1. 1.Department of OrthopaedicsThe First Affiliated Hospital of Soochow UniversitySuzhou, JiangsuChina
  2. 2.Department of Orthopaedics, Changhai HospitalThe Second Military Medical UniversityShanghaiChina
  3. 3.Department of Orthopaedics, Wuxi People’s HospitalNanjing Medical UniversityWuxi, JiangsuChina

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