Mechanical characterization of electrospun gelatin scaffolds cross-linked by glucose

  • Kaido Siimon
  • Hele Siimon
  • Martin Järvekülg
Biomaterials Synthesis and Characterization
Part of the following topical collections:
  1. Biomaterials Synthesis and Characterization


Nanofibrous gelatin scaffolds were prepared by electrospinning from aqueous acetic acid and cross-linked thermally by glucose. The effect of the amount of glucose used as cross-linking agent on the mechanical properties of gelatin fibres was studied in this paper. The elastic modulus of gelatin fibres cross-linked by glucose was determined by modelling the behaviour of the meshes during tensile test. The model draws connections between the elastic moduli of a fibrous mesh and the fibre material and allows evaluation of elastic modulus of the fibre material. It was found that cross-linking by glucose increases the elastic modulus of gelatin fibres from 0.3 GPa at 0 % glucose content to 1.1 GPa at 15 % glucose content. This makes fibrous gelatin scaffolds cross-linked by glucose a promising material for biomedical applications.


Elastic Modulus Tensile Test Gelatin Fibre Diameter Fibre Material 
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This study was financially supported by the European Union through the European Regional Development Fund via projects “Carbon Nanotube Reinforced Electrospun Nano-fibres and Yarns” (3.2.1101.12-0018), “SmaCell” (3.2.1101.12-0017) and Centre of Excellence “Mesosystems: Theory and Applications” (3.2.0101.11-0029) and Estonian Science Foundation Grant IUT2-25.


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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • Kaido Siimon
    • 1
  • Hele Siimon
    • 1
  • Martin Järvekülg
    • 1
    • 2
  1. 1.Institute of PhysicsUniversity of TartuTartuEstonia
  2. 2.Estonian Nanotechnology Competence CenterTartuEstonia

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