Journal of Materials Science: Materials in Medicine

, Volume 23, Issue 12, pp 2831–2837 | Cite as

Microwave assisted synthesis of amorphous magnesium phosphate nanospheres

  • Huan Zhou
  • Timothy J. F. Luchini
  • Sarit B. Bhaduri


Magnesium phosphate (MgP) materials have been investigated in recent years for tissue engineering applications, attributed to their biocompatibility and biodegradability. This paper describes a novel microwave assisted approach to produce amorphous magnesium phosphate (AMP) in a nanospherical form from an aqueous solution containing Mg2+ and HPO4 2−/PO4 3−. Some synthesis parameters such as pH, Mg/P ratio, solution composition were studied and the mechanism of AMP precursors was also demonstrated. The as-produced AMP nanospheres were characterized and tested in vitro. The results proved these AMP nanospheres can self-assemble into mature MgP materials and support cell proliferation. It is expected such AMP has potential in biomedical applications.


Simulated Body Fluid Bone Cement Tissue Engineering Application Akermanite MgHPO4 
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Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  • Huan Zhou
    • 1
  • Timothy J. F. Luchini
    • 1
  • Sarit B. Bhaduri
    • 1
    • 2
  1. 1.Department of Mechanical, Industrial and Manufacturing EngineeringUniversity of ToledoToledoUSA
  2. 2.Dentistry, Department of SurgeryUniversity of ToledoToledoUSA

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