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Preparation and antimicrobial activity of poly (vinyl chloride)/gelatin/montmorillonite biocomposite films

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Abstract

The aim of this study was using a novel antimicrobial thermoplastic plasticizer based on aliphatic anhydride derivative dodecenyl succinic anhydride (DSA) for blending poly (vinyl chloride), PVC, with gelatin in presence of montmorillonite (MMT) using Brabender via polymer melting technique. This anhydride-based plasticizer blended the membrane ingredients homogenously under melting process. The used plasticizer exhibited high performance antimicrobial potency for some biomedical and industrial applications. The prepared biocomposite films were evaluated for antimicrobial activity using agar disc diffusion method against gram-positive and gram-negative bacteria such as: Staphylococcus aureus (S. aureus), Klebsiella pneumonia (K. pneumonia), Bacillus cereus (B. cereus), Bacillus subtilis (B. subtilis) and Escherichia coli (E. coli). The majority of these biocomposites, except the plasticized PVC with DOP, have shown inhibitory effect at different concentrations (1.0–20) mg/ml against all above mentioned bacteria. However, C. albicans and A. niger were the most resistant strains.

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Acknowledgment

Authors wish to thank Center of Molecular and Macromolecular studies, Polish Academy of Sciences, Poland, for generous assistance to carry out some experiments (2DXRD) in this study during the scientific visit of one of the author (Ahmed A. Haroun).

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Authors and Affiliations

  1. Chemical Industries Research Division, National Research Center, Dokki, Egypt

    Ahmed A. Haroun

  2. Department of Natural and Microbial Products, National Research Center, Dokki, Egypt

    Eman F. Ahmed

  3. Department of Polymers and Pigments, National Research Center, Dokki, Egypt

    M. A. Abd El-Ghaffar

Authors
  1. Ahmed A. Haroun
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  2. Eman F. Ahmed
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  3. M. A. Abd El-Ghaffar
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Correspondence to Ahmed A. Haroun.

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Haroun, A.A., Ahmed, E.F. & Abd El-Ghaffar, M.A. Preparation and antimicrobial activity of poly (vinyl chloride)/gelatin/montmorillonite biocomposite films. J Mater Sci: Mater Med 22, 2545–2553 (2011). https://doi.org/10.1007/s10856-011-4437-x

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  • DOI: https://doi.org/10.1007/s10856-011-4437-x

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