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Journal of Materials Science: Materials in Medicine

, Volume 18, Issue 9, pp 1771–1779 | Cite as

Influence of polyelectrolyte on the thermosensitive property of PNIPAAm-based copolymer hydrogels

  • Xian-Zheng Zhang
  • Chih-Chang Chu
Article

Abstract

A new family of poly(NIPAAm-co-2-acrylamido-2-methyl-1-propanesulfonic acid) [P(NIPAAm-co-AMPSA)] hydrogels was synthesized by incorporating negative charged AMPSA to the backbone of the PNIPAAm-based hydrogel. The effect of polyelectrolyte (i.e., PAMPSA) on the thermosensitive property of PNIPAAm hydrogels was investigated. It was found that P(NIPAAm-co-AMPSA) hydrogels exhibited unique honey-comb-like 3D porous structure having rigid cell wall as well as enhanced mechanical property. The incorporation of AMPSA into PNIPAAm backbones also led to a significant increase in swelling capability at room temperature when comparing to pure PNIPAAm hydrogels. In addition, the shrinking rate upon heating was significantly improved if the AMPSA content in P(NIPAAm-co-AMPSA) hydrogels was less than 10 wt%.

Keywords

Lower Critical Solution Temperature PNIPAAm Feed Ratio Hydrogel Sample Copolymer Hydrogel 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  1. 1.Key Laboratory of Biomedical Polymers of Ministry of Education & Department of ChemistryWuhan UniversityWuhanP.R. China
  2. 2.Department of Textiles and Apparel & Biomedical Engineering ProgramCornell UniversityIthacaUSA

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