Synthesis and characterization of hydroxyapatite by microwave heating using CaSO4·2H2O and Ca(OH)2 as calcium source



In this paper, synthesis of hydroxyapatite (HAp) in the absence or presence of 1.05 wt% magnesium oxide, as sintering additive, by heating in a microwave oven was studied. For this purpose, CaSO4·2H2O, Ca(OH)2, Mg(OH)2 and (NH4)2HPO4 were used as raw materials. The total chemical reactions for all the studied compositions were observed after a 3 h microwave treatment. In case of pure hydroxyapatite, a powder with needle-like grains results. In the presence of Mg(OH)2, the (Mg, Ca2)·O·(HPO4)2·H2O hydrated phosphate is formed besides hydroxyapatite. Pure hydroxyapatite, thermally treated at 1,200 °C, mostly transforms in β-Ca3P2O8. By adding MgO into the precursor mixture, hydroxyapatite was stabilised, and found in a much greater proportion at 1,200 °C. After the thermal treatment, the hydroxyapatite, analysed by electronic microscopy, shows a prismatic morphology originating in its initial state.


Hydroxyapatite CaSO4 Microwave Heating Magnesium Hydroxide Tricalcium Phosphate 
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© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  1. 1.Science and Engineering of Oxide Materials and NanomaterialsPolitehnica University of BucharestBucharestRomania

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