Fluorapatite-mullite glass sputter coated Ti6Al4V for biomedical applications

  • J. K. Bibby
  • N. L. Bubb
  • D. J. Wood
  • P. M. Mummery


A number of bioactive ceramics have been researched since the development of Bioglass in the 1970’s. Fluorapatite mullite has been developed from the dental glass-ceramics used for more general hard tissue replacement. Being brittle in nature, glass-ceramics are currently used mainly as coatings. This paper shows that fluorapatite glass LG112 can be used as a sputtered glass coating on roughened surfaces of Ti6Al4V for possible future use for medical implants. An AFM was used to measure the roughness of the surface before and after coating to determine the change in the topography due to the coating process as this greatly affects cell attachment. The sputter coating partially filled in the artificially roughened surface, changing the prepared topography. Osteoblasts have been successfully grown on the surface of these coatings, showing biocompatibility with bone tissue and therefore potential use in hard tissue repair.


Polymer Roughened Surface Brittle Bone Tissue Biomedical Application 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    D. T. Mc DONALD, F. BUTTS, M. STRANICK, S. DOTY and A. L. BOSKEY, J. Biomed. Mater. Res. 54(4) (2001) 480.CrossRefPubMedGoogle Scholar
  2. 2.
    L. L. HENCH and J. WILSON, ‘Introduction to Bioceramics’ (World Scientific, 1993).Google Scholar
  3. 3.
    C. MASSARO, M. A.BAKER, F. COSENTINO, P. A. RAMIRES, S. KLOSE and E. MILELLA, J. Biomed. Mater. Res. 58 (2001) 651.CrossRefPubMedGoogle Scholar
  4. 4.
    V. SAMPATHKUMARAN and M. R. De GUIRE, Adv. Eng. Mater. 6 (2001) 401.CrossRefGoogle Scholar
  5. 5.
    H. C. GLEDHILL, I. G. TURNER and C. DOYLE, Biomaterials 22(11) (2001) 1233.CrossRefPubMedGoogle Scholar
  6. 6.
    C. JANA, P. WANGE, G. GRIMM and W. GOTZ, Glass. Sci. Technol. 68(4) (1995) 117.Google Scholar
  7. 7.
    J. M GOMEZ-VEGA, E. SAIZ and A. P. TOMSIA, J. Biomed. Mater. Res. 46(4) (1999) 549.CrossRefPubMedGoogle Scholar
  8. 8.
    C. X. WANG, Z. Q. CHEN and M. WANG, J. Mater. Sci. Mat. Med. 13 (2002) 247.CrossRefGoogle Scholar
  9. 9.
    K. De GROOT, J. G. C. WOLKE and J. A. JANSEN, Jl. Oral. Implant. 20 (1994) 232.Google Scholar
  10. 10.
    L. SUN, C. C. BERNDT, K. A. GROSS and A. KUCUK, J. Biomed. Mater. Res. 58(5) (2001) 570.CrossRefPubMedGoogle Scholar
  11. 11.
    A. M. EKTESSABI and H. KIMURA, Thin Solid Films 270 (1995) 335.CrossRefGoogle Scholar
  12. 12.
    A. BOYD, M. AKAY and B. J. MEENAN, Surf. Interf. Anal. 35 (2003) 188.CrossRefGoogle Scholar
  13. 13.
    A. M. EKTESSAKI, Nuc. Instrum. Meth. B 127/128 (1997) 1008.Google Scholar
  14. 14.
    S. LISTE, P. GONZALEZ, J. SERRA, J. P. BORRAJO, S. CHIUSSI, B. LEON, M. PEREZ-AMOR, J. GARCIA LOPEZ, F. J. FERRER, Y. MORILLA and M. A. RESPALDIZA, Thin Solid Films 453/454 (2004) 219.CrossRefGoogle Scholar
  15. 15.
    K. OZEKI, T. YUHTA, Y. FUKUI, H. AOKI and I. NISHIMURA, J. Mater. Sci. Mat. Med. 13 (2002) 253.CrossRefGoogle Scholar
  16. 16.
    F. HORGAN and B. J. MEENAN, Key. Eng. Mat. 240–242 (2003) 433.Google Scholar
  17. 17.
    Animal Cell Culture—A Practical Approach,” edited by R. I. Freshney (IRL Press, 1986).Google Scholar
  18. 18.
    N. PRICE, S. P. BENDALL, C. FRONDOZA and R. H. JINNAH, J. Biomed. Mater. Res. 37 (1997) 394.CrossRefPubMedGoogle Scholar
  19. 19.
    N. OLMO, A. MARTIN, A. SALINAS, J. TURNAY, M. VALLET-REGA and M. A. LIZARBE, Biomaterials 24(20) (2003) 3383.CrossRefPubMedGoogle Scholar
  20. 20.
    K. ANSELME, P. LINEZ, M. BIGERELLE, D. Le MAGUER, A. Le MAGUER and P. HARDOUIN, ibid. 21 (2000) 1567.CrossRefPubMedGoogle Scholar
  21. 21.
    A. EL-GHANNAM, E. HAMAZAWY and A. YEHIA, J. Biomed. Mater. Res. 55 (2001) 387.CrossRefPubMedGoogle Scholar
  22. 22.
    K. MATSUZAKA, X. F. WALBOOMERS, M. YOSHINARI, T. INOUE and J. A. JANSEN, Biomaterials 24 (2003) 2711.CrossRefPubMedGoogle Scholar
  23. 23.
    M. YOSHINARI, K. MATSUZAKA, T. INOUE and Y.ODA, J. Biomed. Mater. Res. 65A (2003) 359.CrossRefGoogle Scholar
  24. 24.
    M. BIGERELLE, K. ANSELME, B. NOEL, I. RUDEMAN, P. HARDOUIN and A. IOST, Biomaterials 23 (2002) 1563.CrossRefPubMedGoogle Scholar
  25. 25.
    K. MATSUZAKA, X. F. WALBOOMERS, M. YOSHINARI, T. INOUE AND J. A. JANSEN, ibid. 24 (2003) 2711.CrossRefPubMedGoogle Scholar
  26. 26.
    M. YOSHINARI, K. MATSUZAKA, T. INOUE, Y.ODA and M. SHIMONO, J. Biomed. Mater. Res. 65A (2003) 359.CrossRefGoogle Scholar
  27. 27.
    R. HILL, A. RAFFERTY and DAVID J. WOOD, Glass. Sci. Technol. 73 (2000) 146.Google Scholar

Copyright information

© Springer Science + Business Media, Inc. 2005

Authors and Affiliations

  • J. K. Bibby
    • 1
  • N. L. Bubb
    • 2
  • D. J. Wood
    • 2
  • P. M. Mummery
    • 1
  1. 1.School of MaterialsUniversity of ManchesterManchester
  2. 2.Department of Oral BiologyUniversity of Leeds

Personalised recommendations