Study on the Inclusion Compounds of Eugenol with α-, β-, γ- and Heptakis (2,6-di-O-methyl)-β-cyclodextrins
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Several host–guest inclusion compounds of eugenol as a guest molecule and cyclodextrins (α-,β-,γ-CD) and heptakis (2,6-di-O-methyl)-β-cyclodextrin (DMβ-CD) as hosts were investigated in the solid state and in aqueous solution. The one-to-one solid inclusion compounds of eugenol and β-CD or γ-CD were prepared, but those of eugenol with α- or DMβ-CD were not obtained under the same condition. However, the UV-visible absorption spectroscopy data indicated that the liquid guest could form a 1:1 inclusion compound with all four hosts respectively in aqueous solution. The two solid inclusion compounds were characterized by powder X-ray diffraction (XRD), infrared spectroscopy (IR), thermogravimetric analysis (TG), differential scanning calorimetry (DSC) and nuclear magnetic resonance (NMR). The association constants (K), calculated from the modified Benesi–Hidebrand equation, of eugenol with α-, β-, γ- and DMβ-CD is 4.95 × 104, 3.96 × 105, 1.47 × 105 and 9.33 × 104 mol−1 dm3, respectively.
Keywordscyclodextrin eugenol heptakis(2 6-di-O-methyl)-β- inclusion compound
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- 1.J. Szejtli. Cyclodextrin Technology. Kluwer Academic Publishers (1988)Google Scholar
- 2.Song, L.X. 2001Acta Chim. Sinica591201Google Scholar
- 3.Song, L.X., Guo, Z.J. 2001Chin. J. Inorg. Chem .17457Google Scholar
- 5.Harata, K, Song, LX., Morii, H. 2000Supramol. Chem.11217Google Scholar
- 10.Song, LX., Tu, Z., Zhao, L., Guo, Z.J. 2002Chin. J. Inorg. Chem.18518Google Scholar
- 11.Song, LX., Keng, X., Guo, Z.J. 2002Acta Chim. Sinica601419Google Scholar
- 14.Song, LX., Meng, QJ., You, X.Z. 1996Acta Chim. Sinica54777Google Scholar
- 18.Song, LX., Li, BL., Jiang, R., Ding, JG., Meng, Q.J. 1997Chin. Chem. Lett.8613Google Scholar
- 19.lewis, E.A., Hansen, L.D. 1973J. Chem. Soc., Perkin Trans.22081Google Scholar