Uncommon Interactions of Aliphatic Dicarboxylic Acids with Cyclodextrins

  • Orsolya Csernák
  • Ágnes Buvári-barcza
  • János Samu
  • Lajos Barcza


A relatively high and unexpected increase of inclusion complex stabilities could be detected in some half dissociated dicarboxylic acids (HA ions) with intramolecular H-bonding. The intermolecular hydrogen bonds between the protruding functional groups of the guest and the hydroxy groups of the host are known to enhance the stability of the cyclodextrin (CD) inclusion complexes. The enhanced inclusion of HA species is promoted, not by the intermolecular but by the intramolecular H-bond indirectly, resulting in a compact shape of the guest with more favourable space filling.


Cyclodextrin complexes Dicarboxylic acids Intramolecular hydrogen bond 


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Copyright information

© Springer 2005

Authors and Affiliations

  • Orsolya Csernák
    • 1
  • Ágnes Buvári-barcza
    • 1
  • János Samu
    • 2
  • Lajos Barcza
    • 1
  1. 1.Department of Inorganic and Analytical ChemistryL. Eötvös UniversityHungary
  2. 2.Department of Organic ChemistryL. Eötvös UniversityBudapestHungary

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