Skip to main content
Log in

Electrical isolation of the superior vena cava by laser balloon ablation in patients with atrial fibrillation

  • Published:
Journal of Interventional Cardiac Electrophysiology Aims and scope Submit manuscript

Abstract

Purpose

The aim of the present study is to evaluate the feasibility and safety of SVC electrical isolation by LB ablation in patients with atrial fibrillation (AF) referred for pulmonary vein isolation (PVI).

Methods

Electrical disconnection of the SVC was attempted by LB in 13 consecutive patients (59 ± 10.5 years, 11 male) with AF following PVI. PVI was successfully achieved by standard LB in all before attempting SVC isolation.

Results

A laser beam was delivered with 6.3 ± 2.3 W and 8.4 ± 2.7 W (P = 0.001) during 5.38 ± 2.4 min and 9.75 ± 1.6 min (P = 0.024) to achieve SVC and PV, respectively. Isolation of the SVC by LB was accomplished in 8 patients (61%) without complications. Phrenic nerve palsy developed in 3 patients (23%), which resulted in early procedure termination before isolation. Technical problems or interposition of a pacemaker lead to prevented SVC isolation in the remaining 2 patients. After a mean follow-up of 19 ± 3 months, no patient recovered from phrenic nerve palsy.

Conclusions

SVC isolation by LB is feasible but associated with a high risk of phrenic nerve palsy. Limitation of laser delivery time and power appears insufficient to prevent this complication.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  1. Terasawa T, Balk EM, Chung M, Garlitski AC, Alsheikh-Ali AA, Lau J, et al. Systematic review: comparative effectiveness of radiofrequency catheter ablation for atrial fibrillation. Ann Intern Med. 2009;151(3):191–202.

    Article  Google Scholar 

  2. Noheria A, Kumar A, Wylie J, Josephson ME. Catheter ablation vs antiarrhythmic drug therapy for atrial fibrillation: a systematic review. Arch Intern Med. 2008;168(6):581–6.

    Article  Google Scholar 

  3. Cappato R, Calkins H, Chen SA, Davies W, Iesaka Y, Kalman J, et al. Updated worldwide survey on the methods, efficacy, and safety of catheter ablation for human atrial fibrillation. Circ Arrhythm Electrophysiol. 2010;3(1):32–8.

    Article  Google Scholar 

  4. Andrade JG, Khairy P, Guerra PG, Deyell MW, Rivard L, Macle L, et al. Efficacy and safety of cryoballoon ablation for atrial fibrillation: a systematic review of published studies. Heart Rhythm. 2011;8(11):1828.

    Article  Google Scholar 

  5. Kojodjojo P, O’Neill MD, Lim PB, Malcolm-Lawes L, Whinnett ZI, Salukhe TV, et al. Pulmonary venous isolation by antral ablation with a large cryoballoon for treatment of paroxysmal and persistent atrial fibrillation: medium-term outcome and nonrandomised comparison with pulmonary venous isolation by radiofrequency ablation. Heart. 2010;96(17):1379–84.

    Article  Google Scholar 

  6. Gerstenfeld EP, Ren JF, Marchlinski FE. Atrial tachycardia successfully treated by electrical isolation of the superior vena cava. Pacing Clin Electrophysiol. 2003;26:906–10.

    Article  Google Scholar 

  7. Arruda M, Mlcochova H, Prasad SK, Kilicaslan F, Saliba W, Patel D, et al. Electrical isolation of the superior vena cava: an adjunctive strategy to pulmonary vein antrum isolation improving the outcome of AF ablation. J Cardiovasc Electrophysiol. 2007;18(12):1261–6.

    Article  Google Scholar 

  8. Nademanee K, McKenzie J, Kosar E, Schwab M, Sunsaneewitayakul B, Vasavakul T, et al. A new approach for catheter ablation of atrial fibrillation: mapping of the electrophysiologic substrate. J Am Coll Cardiol. 2004;43:2044–53.

    Article  Google Scholar 

  9. Tsai CF, Tai CT, Hsieh MH, Lin WS, Yu WC, Ueng KC, et al. Initiation of atrial fibrillation by ectopic beat originating from superior vena cava; electrophysiological characteristics and results of radiofrequency ablation. Circulation. 2000;102:67–74.

    Article  CAS  Google Scholar 

  10. Merino JL, Peinado R, Abello M, Gnoatto M, Vasserot MG, Sobrino JA. Superior vena cava flutter: electrophysiology and ablation. J Cardiovasc Electrophysiol. 2005 Jun;16(6):568–75.

    Article  Google Scholar 

  11. Haïssaguerre M, Hocini M, Sanders P, et al. Catheter ablation of long-lasting persistent atrial fibrillation: clinical outcome and mechanism of subsequent arrhythmias. J Cardiovasc Electrophysiol. 2005;16(11):1138–47.

    Article  Google Scholar 

  12. Ejima K, Kato K, Iwanami Y, Henmi R, Yagishita D, Malaka T, et al. Impact of an empiric isolation of the superior vena cava in addition to circumferential pulmonary vein isolation on the outcome of paroxysmal atrial fibrillation ablation. Am J Cardiol. 2015;116(11):1711–6.

    Article  Google Scholar 

  13. Murat S, Kudret A, Hikmet Y. Innappropriate sinus tachycardia after superior vena cava isolation in addition to pulmonary veins Isolatin of paroxysmal atrial fibrillation cryoballoon ablation. J Atr Fibrillation. 2015;8(2):1270.

    Google Scholar 

  14. Schmidt B, Metzner A, Chun KR, Leftheriosis D, Yoshiga Y, Fuernkranz A, et al. Feasibility of circumferential pulmonary vein isolation using a novel endoscopic ablation system. Circ Arrhythm Electrophysiol. 2010;3(5):481–8.

    Article  Google Scholar 

  15. Hsieh MH, Chen SA. Is it necessary to routinely perform isolation of the superior vena cava in every atrial fibrillation patients? J Cardiovasc Electrophysiol. 2007;18:1267–8.

    Article  Google Scholar 

  16. Corrado A, Bonso A, Madalosso M, Rosillo A, Themistoclakis S, Di Biase L, et al. Impact of systematic isolation of superior vena cava in addition to pulmonary vein antrum isolation on the outcome of paroxysmal, persistent, and permanent atrial fibrillation ablation: results from a randomized study. J Cardiovasc Electrophysiol. 2010;21(1):1–5.

    Article  Google Scholar 

  17. Wang XH, Liu X, Sun YM, Shi HF, Zhou L, Gu JN. Pulmonary vein isolation combined with superior vena cava isolation for atrial fibrillation ablation: a prospective randomized study. Europace. 2008;10(5):600–5.

    Article  CAS  Google Scholar 

  18. Dib C, Kapa S, Powell B, Packer D, Asirvatham S. Successful use of “cryo-mapping” to avoid phrenic nerve damage during ostial superior vena caval ablation despite nerve proximity. J Interv Card Electrophysiol. 2008;22:23–30.

    Article  Google Scholar 

  19. Sacher F, Monahan KH, Thomas SP, Davidson N, Adragao P, Sanders P, et al. Phrenic nerve injury after atrial fibrillation catheter ablation. J Am Coll Cardiol. 2006;47:2498–503.

    Article  Google Scholar 

  20. Miyazaki S, Usui E, Kusa S, Taniguchi H, Ichihara N, Takagi T, et al. Prevalence and clinical outcome of phrenic nerve injury during superior vena cava isolation and circumferential pulmonary vein antrum isolation using radiofrequency energy. Am Heart J. 2014;168:846–53.

    Article  Google Scholar 

  21. Linhart M, Nielson A, Andrié RP, Mittmann-Braun EL, Stöckigt F, Kreuz J, et al. Fluoroscopy of spontaneous breathing is more sensitive than phrenic nerve stimulation for detection of right phrenic nerve injury during cryoballoon ablation of atrial fibrillation. J Cardiovasc Electrophysiol. 2014;25:859–65.

    Article  Google Scholar 

  22. Miyazaki S, Hachiya H, Taniguchi H, Nakamura H, Ichihara N, Usui E, et al. Prospective evaluation of bilateral diaphragmatic electromyograms during cryoballooon ablation of atrial fibrillation. J Cardiovasc Electrophysiol. 2015;26:622–8.

    Article  Google Scholar 

  23. Dukkipati SR, Kuck KH, Neuzil P, Woollett I, Kautzner J, Mc Elderry HT, et al. Pulmonary vein isolation using a visually guided laser balloon catheter: the first 200-patient multicenter clinical experience. Circ Arrhythm Electrophysiol. 2013;6(3):467–72.

    Article  Google Scholar 

  24. Bordignon S, Chun KR, Gunawardene M, Fuernkranz A, Urban V, Schulte-Hahn B, et al. Comparison of balloon catheter ablation technologies for pulmonary vein isolation: the laser versus cryo study. J Cardiovasc Electrophysiol. 2013;24(9):987–94.

    Article  Google Scholar 

  25. Bunch TJ, Bruce GK, Mahapatra S, Johnson SB, Miller DV, Sabanda AV, et al. Mechanisms of phrenic nerve injury during radiofrequency ablation at the pulmonary vein orifice. J Cardiovasc Electrophysiol. 2005;16:1318–25.

    Article  Google Scholar 

  26. Arceluz MR, Merino JL, Cruz F, Falconi E, Salvador O, Figueroa J, et al. Pulmonary vein isolation by laser balloon ablation: is energy delivered too deep into the vein? (Abstract). Eur Heart J. 2016;37(Issue suppl_1, 1 August):1084.

    Google Scholar 

Download references

Acknowledgments

We acknowledge Kathleen Johanna Mc Ewen for the linguistic revision of the article.

Author information

Authors and Affiliations

Authors

Contributions

Data Collection: Pedro F. Cruz, Estela Falconi, Rosa Montes de Oca, Reina, Delgado, Jorge Figueroa, Marta Ortega.

Critical revision of Article: José L. Merino.

Corresponding authors

Correspondence to Martín R. Arceluz or José L. Merino.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Arceluz, M.R., Cruz, P.F., Falconi, E. et al. Electrical isolation of the superior vena cava by laser balloon ablation in patients with atrial fibrillation. J Interv Card Electrophysiol 53, 217–223 (2018). https://doi.org/10.1007/s10840-018-0380-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10840-018-0380-9

Keywords

Navigation