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Efficacy of advanced pace-mapping technology for idiopathic premature ventricular complexes ablation

  • J. Fedida
  • T. Strisciuglio
  • M. Sohal
  • M. Wolf
  • K. Van Beeumen
  • A. Neyrinck
  • P. Taghji
  • C. Lepiece
  • A. Almorad
  • Y. Vandekerckhove
  • R. Tavernier
  • M. Duytschaever
  • S. Knecht
Article
  • 160 Downloads

Abstract

Purpose

Catheter ablation is an effective treatment for premature ventricular complexes (PVCs). Activation mapping is accurate but requires PVCs at the time of the ablation. Pace-mapping correlation (PMC) is a supplemental tool recently developed as an integrated module for an electro-anatomical mapping platform. Our study sought to investigate whether pace-mapping technology provides similar ablation results in patients with low versus high idiopathic PVC burden at the time of ablation and the relationship between sites with the highest PMC and the earliest local activation time (LAT).

Methods

A total of 59 consecutive patients undergoing catheter ablation for idiopathic PVCs were enrolled. Twelve out of 59 patients (20%) were classified in the low PVC burden group (defined as < 2 PVCs/min) and 47/59 (80%) in the high PVC burden group.

Results

The most common origin of PVCs was the right ventricular outflow tract (RVOT) followed by aortic cusps, coronary sinus, parahisian region, and aorto-mitral continuity. Procedural and 1-month success rate were 95 and 87% respectively. PVC burden at the time of ablation did not influence the success rate. The median distance between the earliest LAT points and the highest PMC points was 6.4 (4.9–10.6) mm.

Conclusions

Pace-mapping correlation is useful and accurate in localizing the origin of idiopathic PVCs irrespective of the initial PVC burden. It provides optimal ablation results when combined with LAT. Success rate at mid-term follow-up is higher when the origin of PVCs is located in the RVOT as compared to other locations.

Keywords

Premature ventricular complexes Catheter ablation Pace mapping Local activation time 

Notes

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • J. Fedida
    • 1
    • 2
    • 3
  • T. Strisciuglio
    • 1
    • 4
  • M. Sohal
    • 5
  • M. Wolf
    • 1
  • K. Van Beeumen
    • 1
  • A. Neyrinck
    • 1
  • P. Taghji
    • 1
  • C. Lepiece
    • 6
  • A. Almorad
    • 1
  • Y. Vandekerckhove
    • 1
  • R. Tavernier
    • 1
  • M. Duytschaever
    • 1
  • S. Knecht
    • 1
  1. 1.CardiologySt-Jan HospitalBrugesBelgium
  2. 2.Hopital Pitié-Salpêtrière, Paris 6 Sorbonne Université, Institut de CardiologieParisFrance
  3. 3.Département de Cardiologie, AP-HPHôpital Pitié-SalpêtrièreParisFrance
  4. 4.University of Naples Federico IINaplesItaly
  5. 5.CardiologyGeorge’s Healthcare NHS TrustLondonUK
  6. 6.Hopital de JolimontLa LouvièreBelgium

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