Site localization of painful lesions during radiofrequency ablation of pulmonary veins using circular multi-electrode catheters

  • Avishag Laish-FarkashEmail author
  • Amos Katz
  • Ornit Cohen
  • Azriel Osherov
  • Sharon Bruocha
  • Vladimir Khalameizer



Previous data showed that pain sensation was common during pulmonary vein isolation (PVI) using an 8-mm radiofrequency (RF) ablation catheter. Pain was more common in the left pulmonary veins (PVs). We characterized the location of pain during PVI using circular multi-electrode ablation catheters.


Included are all consecutive patients with atrial fibrillation (AF) who underwent PVI using the phased RF PVAC® catheter (Medtronic) or the irrigated nMARQ™ catheter (Biosense Webster) under conscious sedation between July 2011 and March 2015. Site of pain reaction was marked for each patient.


A total of 251 patients (141 PVAC®, 110 nMARQ™) were studied; 214 (85 %) had at least one lesion associated with pain. Gender (r = 0.084, p = 0.186), type of AF (r = 0.048, p = 0.452), age (r = 0.078, p = 0.216), and repeat procedure (r = 0.018, p = 0.78) were not correlated with pain. There was no association between site of pain and catheter type; only 33 % of the painful PVs were also the largest ones (p = 0.5, kappa = 0.03, R = −0.083). One-year freedom from AF was similar for patients with and without painful PVs (p = 0.6). The distribution of pain was as follows: 126 (59 %) left superior PV (LSPV), 28 (13 %) left inferior, 28 (13 %) all PVs, 12 (5.6 %) right superior, 12 (5.6 %) right inferior, 18 (8.4 %) left common, and 2 (0.9 %) right common PV.


PVI using multi-electrode catheters more commonly caused pain sensation in LSPV. There was no influence of catheter type or PV size on pain localization. Our findings, which are similar to those using an 8-mm ablation catheter, imply that location of pain is not catheter dependent but rather a reflection of autonomic physiology.


Atrial fibrillation Ablation Circular multi-electrode catheter Pain Pulmonary veins 



No financial support was received for this study.

Compliance with ethical standards

The study protocol was approved by our institution review board and was not influenced by Medtronic or Biosense Webster companies.

Informed consent

All patients provided an informed consent prior to the procedure.


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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • Avishag Laish-Farkash
    • 1
    • 2
    Email author
  • Amos Katz
    • 1
    • 2
  • Ornit Cohen
    • 1
    • 2
  • Azriel Osherov
    • 1
    • 2
  • Sharon Bruocha
    • 1
    • 2
  • Vladimir Khalameizer
    • 1
    • 2
  1. 1.Electrophysiology Unit, Cardiology DepartmentBarzilai Medical CenterAshkelonIsrael
  2. 2.Faculty of Health SciencesBen-Gurion University of the NegevBeer-ShevaIsrael

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