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Catheter ablation for atrial fibrillation results in greater improvement in cardiac function in patients with low versus normal left ventricular ejection fraction

  • Zekeriya Kucukdurmaz
  • Ritsushi Kato
  • Alim Erdem
  • Ebru Golcuk
  • Takeshi Tobiume
  • Takahiko Nagase
  • Yoshifumi Ikeda
  • Yoshie Nakajima
  • Makoto Matsumura
  • Nobuyuki Komiyama
  • Shigeyuki Nishimura
  • Kazuo Matsumoto
Article

Abstract

Purpose

It is still unknown whether left ventricular ejection fraction (LVEF) might affect the magnitude of improvement after atrial fibrillation (AF) ablation on cardiac function in persistent or longstanding persistent AF (CAF) patients.

Method

We performed echocardiography in 35 patients with CAF before and after catheter ablation (CA). Patients were stratified by LVEF into two groups prior to CA—normal LVEF (≥50 % LVEF, N group, n = 24) and a low LVEF group (<50 % LVEF, L group, n = 11). Patients were followed at 1 month, 3 months, 6 months, 1 year, and 2 years after ablation.

Results

After 15.8 ± 7.4 months follow-up, the L group showed greater improvement in LVEF and left atrial ejection fraction (LAEF; N group vs L group: LVEF difference (%), 5 ±8 vs 20± 13, p < 0.01; LAEF difference (%), 11 ± 12 vs 21 ± 10, p < 0.05). LA maximal volume and E/e′ showed the same tendency after ablation, although the extent of improvement was not statistically significant. Both groups showed almost the same time course of improvement up to 2 years, although the L group showed earlier recovery in LVEF.

Conclusion

The greater improvement in several cardiac functions was seen in patients with greater LV dysfunction, after the CA for CAF.

Keywords

Atrial fibrillation Catheter ablation Cardiac function Echocardiography Low LVEF 

Abbreviations

AF

Atrial fibrillation

CAF

Persistent or longstanding persistent AF

CFAE

Complex fragmented atrial electrogram

LA

Left atrium

LAEF

Left atrial ejection fraction

LVEF

Left ventricular ejection fraction

MDCT

Multidetector computed tomography

PSVT

Paroxysmal supraventricular tachycardia

PV

Pulmonary vein

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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Zekeriya Kucukdurmaz
    • 1
    • 2
  • Ritsushi Kato
    • 2
  • Alim Erdem
    • 1
    • 2
  • Ebru Golcuk
    • 2
  • Takeshi Tobiume
    • 2
  • Takahiko Nagase
    • 2
  • Yoshifumi Ikeda
    • 2
  • Yoshie Nakajima
    • 2
  • Makoto Matsumura
    • 2
  • Nobuyuki Komiyama
    • 2
  • Shigeyuki Nishimura
    • 2
  • Kazuo Matsumoto
    • 2
  1. 1.Department of CardiologyCumhuriyet University Medical SchoolSivasTurkey
  2. 2.Department of CardiologySaitama Medical University, International Medical CenterHidakaJapan

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