Skip to main content

Advertisement

SpringerLink
Log in

Ventricular fibrillation associated with early repolarization in a patient with thyroid storm

  • CASE REPORT
  • Published:
Journal of Interventional Cardiac Electrophysiology Aims and scope Submit manuscript

Abstract

We present a case of a 69-year-old male who was hospitalized for the treatment of thyroid storm due to Grave’s disease, who presented with unexpected ventricular fibrillation (VF). The possible etiology was early repolarization (ER), characterized by J-point elevation in inferior and posterolateral leads, unmasked by the attenuation of beta-adrenergic effect with normalization of thyroid hormones and following the administration of a beta-blocker. Our case focuses attention on the occurrence of VF in a patient with ER during the treatment of hyperthyroidism, which to our knowledge is the first such report.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3

References

  1. Wasserburger, R. H., & Alt, W. J. (1961). The normal RS-T segment elevation variant. The American Journal of Cardiology, 8, 184–192.

    Article  CAS  PubMed  Google Scholar 

  2. Gussak, I., & Antzelevitch, C. (2000). Early repolarization syndrome: clinical characteristics and possible cellular and ionic mechanisms. Journal of Electrocardiology, 33, 299–309.

    Article  CAS  PubMed  Google Scholar 

  3. Haissaguerre, M., Derval, N., Sacher, F., Jesel, L., Deisenhofer, I., de Roy, L., et al. (2008). Sudden cardiac arrest associated with early repolarization. The New England Journal of Medicine, 358, 2016–2023.

    Article  CAS  PubMed  Google Scholar 

  4. Antzelevitch, C., & Yan, G. X. (2010). J wave syndromes. Heart Rhythm, 7, 549–558.

    Article  PubMed  Google Scholar 

  5. Burch, H. B., & Wartofsky, L. (1993). Life-threatening thyrotoxicosis, thyroid storm. Endocrinology and Metabolism Clinics of North America, 22, 263–277.

    CAS  PubMed  Google Scholar 

  6. Geffner, D. L., & Hershman, J. M. (1992). Beta-adrenergic blockade for the treatment of hyperthyroidism. The American Journal of Medicine, 93, 61–68.

    Article  CAS  PubMed  Google Scholar 

  7. Morace, G., Padeletti, L., Porciani, M. C., & Fantini, F. (1979). Effect of isoproterenol on the early repolarization syndrome. American Heart Journal, 97, 343–347.

    Article  CAS  PubMed  Google Scholar 

  8. Shimoni, Y. (1999). Hormonal control of cardiac ion channels and transporters. Progress in Biophysics and Molecular Biology, 72, 67–108.

    Article  CAS  PubMed  Google Scholar 

  9. Shimoni, Y., & Severson, D. L. (1995). Thyroid status and potassium currents in rat ventricular myocytes. The American Journal of Physiology, 268, H576–H583.

    CAS  PubMed  Google Scholar 

  10. Nam, G. B., Ko, K. H., Kim, J., Park, K. M., Rhee, K. S., Choi, K. J., et al. (2010). Mode of onset of ventricular fibrillation in patients with early repolarization pattern vs Brugada syndrome. European Heart Journal, 31, 330–339.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Intensive and Cardiac Care Unit, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 1138603, Japan

    Akira Ueno, Takeshi Yamamoto, Naoki Sato & Keiji Tanaka

Authors
  1. Akira Ueno
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Takeshi Yamamoto
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Naoki Sato
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Keiji Tanaka
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Akira Ueno.

Additional information

We have received no financial support or grants associated with this research.

We have full control of all primary data and agree to allow the journal to review our data if requested.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ueno, A., Yamamoto, T., Sato, N. et al. Ventricular fibrillation associated with early repolarization in a patient with thyroid storm. J Interv Card Electrophysiol 29, 93–96 (2010). https://doi.org/10.1007/s10840-010-9507-3

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10840-010-9507-3

Keywords

Search

Navigation