Journal of Assisted Reproduction and Genetics

, Volume 33, Issue 9, pp 1123–1127 | Cite as

Proceedings of the International Summit on Human Gene Editing: a global discussion—Washington, D.C., December 1–3, 2015

  • Andrew R. LaBarberaEmail author
Meeting Summary


The US Academies of Sciences and Medicine, the Royal Society, and the Chinese Academy of Sciences convened a summit of experts in biology, medicine, law, ethics, sociology, and journalism, in December 2015 to review the state of the art in gene editing technology and discuss the medical and social ramifications of the technologies. The summit concluded with the following consensus recommendations: (1) intensive basic and preclinical research in animal and human models should proceed with appropriate legal and ethical oversight; (2) clinical applications in somatic cells must be rigorously evaluated within existing and evolving regulatory frameworks for gene therapy; (3) it would be irresponsible to proceed with any clinical use of germline editing until relevant safety and efficacy issues have been resolved and there is broad societal consensus about such a use; and (4) the international community should strive to establish generally acceptable uses of human germline editing.


Germline DNA Embryo Stem cells Reproductive rights Inheritable disease 

Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  1. 1.American Society for Reproductive MedicineBirminghamUSA

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