Skip to main content
SpringerLink
Log in

Live birth in a 46 year old using autologous oocytes cryopreserved for a duration of 3 years: a case report documenting fertility preservation at an advanced reproductive age

  • Fertility Preservation
  • Published:
Journal of Assisted Reproduction and Genetics Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Chen C. Pregnancy after human embryo oocyte cryopreservation. Lancet. 1986;1:884–6.

    Article  CAS  PubMed  Google Scholar 

  2. Practice Committee of the Society for Assisted Reproductive Technology, Practice Committee of the American Society for Reproductive Medicine. Ovarian tissue and oocyte cryopreservation. Fertil Steril. 2008;90:S241–6.

    Google Scholar 

  3. Oktay K, Cil AP, Bang H. Efficiency of oocyte preservation: a meta-analysis. Fertil Steril. 2006;86:70–80.

    Article  PubMed  Google Scholar 

  4. Smith JD, Serafini PC, Fioravanti J, Yadid Y, Coslovsky M, Hassun P, et al. Prospective randomized, comparison of human oocyte cryopreservation with slow-rate freezing or vitrification. Fertil Steril. 2010;94:2088–95.

    Article  PubMed  Google Scholar 

  5. Gook DA, Edgar DH. Human oocyte cryopreservation. Human Reprod Update. 2007;13:591–605.

    Article  Google Scholar 

  6. Parmegiani L, Cognigni GE, Bernardi S, Cuomo S, Ciampaglia W, Infante FE, et al. Efficiency of aseptic open vitrification and hermetical cryostorage of human oocytes. Reprod BioMed Online. 2011;23:505–12.

    Article  CAS  PubMed  Google Scholar 

  7. Cobo A, Kuwayama M, Perez S, Ruiz A, Pellicer A, Remohi J. Comparison of concomitant outcome achieved with fresh and cryopreserved donor oocytes vitrified by the Cryotop method. Fertil Steril. 2008;89:1657–64.

    Article  PubMed  Google Scholar 

  8. Rienzi L, Romano S, Albricci L, Maggiulli R, Capalbo A, Baroni E, et al. Embryo development of fresh ‘versus’ vitrified metaphase II oocytes after ICSI: a prospective randomized sibling-oocyte study. Hum Reprod. 2010;25:66–73.

    Article  PubMed Central  PubMed  Google Scholar 

  9. Cobo A, Meseguer M, Remohi J, Pellicer A. Use of cryo-banked oocytes in an ovum donation programme: a prospective, randomized, controlled, clinical trial. Hum Reprod. 2010;25:2239–46.

    Article  PubMed  Google Scholar 

  10. Cobo A, Diaz C. Clinical application of oocyte vitrification: a systematic review and meta-analysis of randomized controlled trials. Fertil Steril. 2011;96:277–85.

    Article  PubMed  Google Scholar 

  11. Noyes N, Porcu E, Borini A. Over 900 oocyte cryopreservation babies born with no apparent increase in congenital abnormalities. Reprod BioMed Online. 2009;18:769–76.

    Article  CAS  PubMed  Google Scholar 

  12. Chian RC, Huang JY, Tan SL, Lucena E, Saa A, Rojas A, et al. Obstetric and perinatal outcome in 200 infants conceived from vitrified oocytes. Reprod BioMed Online. 2008;16:608–10.

    Article  PubMed  Google Scholar 

  13. Practice Committee of the Society for Assisted Reproductive Technology, Practice Committee of the American Society for Reproductive Medicine. Mature oocyte cryopreservation: a guideline. Fertil Steril. 2013;99:37–43.

    Article  Google Scholar 

  14. Borini A, Levi Setti PE, Anserini P, De Luca R, De Santis L, Parcu E, et al. Multicenter observational study on slow-cooling oocyte cryopreservation: clinical outcome. Fertil Steril. 2010;94:1662–8.

    Article  PubMed  Google Scholar 

  15. Bianchi V, Lappi M, Bonu MA, Borini A. Oocyte slow freezing using a 0.2–0.3 M sucrose concentration protocol: is it really the time to trash the cryopreservation machine? Fertil Steril. 2012;97:1101–7.

    Article  CAS  PubMed  Google Scholar 

  16. Rienzi L, Cobo A, Paffoni A, Scarduelli C, Capalbo A, Vajta G, et al. Consistent and predictable delivery rates after oocytes vitrification: an observational longitudinal cohort multicentric study. Hum Reprod. 2012;27:1606–12.

    Article  PubMed  Google Scholar 

  17. Grifo JA, Noyes N. Delivery rate using cryopreserved oocytes is comparable to conventional in vitro fertilization using fresh oocytes: potential fertility preservation for female cancer patients. Fertil Steril. 2010;93:391–6.

    Article  CAS  PubMed  Google Scholar 

  18. Practice Committee of the American Society for Reproductive Medicine, Practice Committee of the Society for Assisted Reproductive Technology. Guidelines on number of embryos transferred. Fertil Steril. 2009;92:1518–9.

    Article  Google Scholar 

  19. Cil AP, Bang H, Oktay K. Age-specific probability of live birth with oocyte cryopreservation: an individual patient data meta-analysis. Fertil Steril. 2013;100:492–9.

    Article  PubMed  Google Scholar 

  20. Yang D, Brown SE, Nguyen K, Reddy V, Brubaker C, Winslow KL. Live birth after the transfer of human embryos developed from cryopreserved oocytes harvested before cancer treatment. Fertil Steril. 2007;87(6):1469.e1–4.

    Article  Google Scholar 

  21. Parmegiani L, Fabbri R, Cognigni GE, Bernardi S, Pocognoli P, Filicori M. Blastocyst formation, pregnancy, and birth derived from human oocytes cryopreserved for 5 years. Fertil Steril. 2008;90(5):2014.e7–10.

    Article  Google Scholar 

  22. Kim TJ, Hong SW. Successful live birth from vitrified oocytes after 5 years of cryopreservation. J Assist Reprod Genet. 2011;28:73–6.

    Article  PubMed Central  PubMed  Google Scholar 

  23. Quintans CJ, Donaldson MJ, Urquiza MF, Carretero I, Pasqualini RA, Horton M, et al. Live birth of twins after IVF of oocytes that were cryopreserved for almost 12 years. Reprod BioMed Online. 2012;25:600–2.

    Article  PubMed  Google Scholar 

  24. La Sala GB, Capodanno F, Valli B, Rondini I, Villani MT, Nicoli A. Live birth from oocytes cryopreserved with slow freezing protocol and thawed after 6 years of storage. J Assist Reprod Genet. 2012;29:277–9.

    Article  PubMed Central  PubMed  Google Scholar 

  25. Ubaldi F, Anniballo R, Romano S, Baroni E, Albricci L, Colamaria S, et al. Cumulative ongoing pregnancy rate achieved with oocyte vitrification and cleavage stage transfer without embryo selection in a standard infertility program. Hum Reprod. 2010;25(5):1199–205.

    Article  PubMed Central  PubMed  Google Scholar 

  26. Goldman KN, Noyes NL, Knopman JM, McCaffrey C, Grifo JA. Oocyte efficiency: does live birth rate differ when analyzing cryopreserved and fresh oocytes on a per-oocyte basis? Fertil Steril. 2013;100(3):712–7.

    Article  PubMed  Google Scholar 

  27. Munné S, Alikani M, Tomkin G, Grifo J, Cohen J. Embryo morphology, developmental rates, and maternal age are correlated with chromosome abnormalities. Fertil Steril. 1995;64(2):382–91.

    PubMed  Google Scholar 

  28. Marquez C, Sandalinas M, Bahce M, Alikani M, Munné S. Chromosome abnormalities in 1255 cleavage-stage human embryos. Reprod BioMed Online. 2000;1:17–26.

    Article  CAS  PubMed  Google Scholar 

  29. Magli MC, Gianaroli L, Ferraretti AP. Chromosomal abnormalities in embryos. Mol Cell Endocrinol. 2001;183(1):S29–34.

    Article  CAS  PubMed  Google Scholar 

  30. Fragouli E, Alfarawati S, Daphnis DD, Goodall NN, Mania A, Griffiths T, et al. Cytogenetic analysis of human blastocyst with the use of FSH, CGH, and aCGH: scientific data and technical evaluation. Hum Reprod. 2011;26:480–90.

    Article  CAS  PubMed  Google Scholar 

  31. Ata B, Kaplan B, Danzer H, Glassner M, Opsahl M, Tan SL, et al. Array CGH analysis shows that aneuploidy is not related with the number of embryos generated. Reprod BioMed Online. 2012;24:614–20.

    Article  CAS  PubMed  Google Scholar 

  32. Harton GL, Munné S, Surrey M, Grifo J, Kaplan B, McCulloh DH, et al. Diminished effect of maternal age on implantation after preimplantation genetic diagnosis with array comparative genomic hybridization. Fertil Steril. 2013;100:1695–703.

    Article  CAS  PubMed  Google Scholar 

  33. Parmegiani L, Garello C, Granella F, Guidetti D, Bernardi S, Cognigni GE, et al. Long term cryostorage does not adversely affect the outcomes of oocyte thawing cycles. Reprod BioMed Online. 2009;19(3):374–9.

    Article  CAS  PubMed  Google Scholar 

  34. Kawwass JF, Monsour M, Crawford S, Kissin DM, Session DR, Kulkarni AD, et al. Trends and outcomes for donor oocyte cycles in the United States, 2000–2010. JAMA. 2013;310(22):2426–34.

    CAS  PubMed  Google Scholar 

  35. Indekeu A, Dierickx K, Schotsmans P, Daniels KR, Rober P, D’Hooghe T. Factors contributing to parental decision-making in disclosing donor conception: a systematic review. Hum Reprod Update. 2013;19(6):714–33.

    Article  CAS  PubMed  Google Scholar 

  36. Blythe E, Kramer W, Schneider J. Perspectives, experiences, and choices of parents of children conceived following oocyte donation. Reprod BioMed Online. 2013;26:179–88.

    Article  Google Scholar 

Download references

Disclosure statement

The authors have nothing to disclose.

Author information

Authors and Affiliations

  1. NYU Langone Medical Center, NYU Fertility Center, 660 First Avenue, New York, NY, 10016, USA

    Susan M. Maxwell, Kara N. Goldman, Patty A. Labella, Caroline McCaffrey, Nicole L. Noyes & James Grifo

Authors
  1. Susan M. Maxwell
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Kara N. Goldman
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Patty A. Labella
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Caroline McCaffrey
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Nicole L. Noyes
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. James Grifo
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Susan M. Maxwell.

Additional information

Capsule This case report documents a live birth in a 46 year old after using autologous oocytes cryopreserved for 3 years. Oocyte cryopreservation is an option for fertility preservation in a select population of patients at an advanced reproductive age.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Maxwell, S.M., Goldman, K.N., Labella, P.A. et al. Live birth in a 46 year old using autologous oocytes cryopreserved for a duration of 3 years: a case report documenting fertility preservation at an advanced reproductive age. J Assist Reprod Genet 31, 651–655 (2014). https://doi.org/10.1007/s10815-014-0202-7

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10815-014-0202-7

Keywords

Search

Navigation