Journal of Assisted Reproduction and Genetics

, Volume 30, Issue 11, pp 1487–1491 | Cite as

Testicular hypoplasia in monochorionic dizygous twin with confined blood chimerism

  • Dong-Hee Choi
  • Hwang KwonEmail author
  • Soong Deok Lee
  • Myoung-Jin Moon
  • Eun-Gyong Yoo
  • Kyu-Hyung Lee
  • Young-Kwon Hong
  • Gwangil Kim


Monochorionic diamniotic (MCDA) twins identified by ultrasound in early pregnancy are rarely dizygotic. Since Shouter et al. first reported that MCDA twin pregnancies can occur in dizygous (DZ) twin pregnancies, there have been about ten reports of such cases [1]. MCDZ twins can be easily overlooked except in cases of discordant sex discovered during prenatal care or delivery of MCDA twins. In our case, chimerism of a set of MCDZ twins was confirmed by STR analysis for both parents and the live male twin after the discovery of discordant sex in a pair of MCDA twins at delivery. Testicular atrophy was suspected in a follow-up sonogram of the testes of the live male twin; Testicular hypoplasia was revealed by a subsequent testicular biopsy. We report herein a rare case of testicular hypoplasia in a male infant with chimerism that was observed on follow-up examination after birth.

Case report

An exemption from the Institutional Review Board (IRB) approval process was obtained...


Short Tandem Repeat Spermatic Cord Testicular Torsion Testicular Biopsy Assisted Reproductive Technique 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Dong-Hee Choi
    • 1
  • Hwang Kwon
    • 1
    Email author
  • Soong Deok Lee
    • 2
  • Myoung-Jin Moon
    • 3
  • Eun-Gyong Yoo
    • 4
  • Kyu-Hyung Lee
    • 4
  • Young-Kwon Hong
    • 5
  • Gwangil Kim
    • 6
  1. 1.CHA Fertility Center of Bundang CHA General Hospital, CHA Research InstituteCHA UniversitySeongnamSouth Korea
  2. 2.Institute of Forensic MedicineSeoul National University College of MedicineSeoulSouth Korea
  3. 3.Department of Obstetrics and Gynecology of Bundang CHA General Hospital, CHA Research InstituteCHA UniversitySeongnamSouth Korea
  4. 4.Department of Pediatrics of Bundang CHA General Hospital, CHA Research InstituteCHA UniversitySeongnamSouth Korea
  5. 5.Department of Urology of Bundang CHA General Hospital, CHA Research InstituteCHA UniversitySeongnamSouth Korea
  6. 6.Department of Pathology of Bundang CHA General Hospital, CHA Research InstituteCHA UniversitySeongnamSouth Korea

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