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Journal of Assisted Reproduction and Genetics

, Volume 29, Issue 3, pp 277–279 | Cite as

Live birth from oocytes cryopreserved with slow-freezing protocol and thawed after 6 years of storage

  • Giovanni Battista La Sala
  • Francesco Capodanno
  • Barbara Valli
  • Ilaria Rondini
  • Maria Teresa Villani
  • Alessia Nicoli
Fertility Preservation

Introduction

After the birth of more than 900 babies from human cryopreserved oocytes with no apparent increase in congenital anomalies compared to conventional IVF babies [1], oocyte cryopreservation has become a quite widespread technique in Assisted Reproductive Technologies (ART), even in the female fertility preservation programs. Today two procedures are available for oocyte cryopreservation: slow-freezing (SF), the first protocol introduced, and vitrification (VT) [2]. The main goal of VT is to achieve high cryoprotectant concentration in order to increase the viscosity of the cryoprotectant solution and to suppress ice nucleation [3]. Biological and clinical outcomes of SF protocols seem to be less than those obtained with fresh and vitrified oocytes [4, 5, 6]. Oocyte cryopreservation is usually used in ART laboratories for supernumerary oocyte storage after Controlled Ovarian Stimulation (COS) [4], prevention of Ovarian HyperStimulation Syndrome (OHSS) risk, oocyte...

Keywords

Assist Reproductive Technology Fertility Preservation Ovarian HyperStimulation Syndrome Embryo Cryopreservation Oocyte Cryopreservation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Conflict of interest

The Authors declare no potential conflict of interests.

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Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  • Giovanni Battista La Sala
    • 1
  • Francesco Capodanno
    • 2
  • Barbara Valli
    • 2
  • Ilaria Rondini
    • 2
  • Maria Teresa Villani
    • 2
  • Alessia Nicoli
    • 2
  1. 1.Department of Obstetrics and GynecologyUniversity of Modena and Reggio EmiliaReggio EmiliaItaly
  2. 2.Department of Obstetrics and GynecologyReggio EmiliaItaly

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