Live birth from oocytes cryopreserved with slow-freezing protocol and thawed after 6 years of storage
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After the birth of more than 900 babies from human cryopreserved oocytes with no apparent increase in congenital anomalies compared to conventional IVF babies , oocyte cryopreservation has become a quite widespread technique in Assisted Reproductive Technologies (ART), even in the female fertility preservation programs. Today two procedures are available for oocyte cryopreservation: slow-freezing (SF), the first protocol introduced, and vitrification (VT) . The main goal of VT is to achieve high cryoprotectant concentration in order to increase the viscosity of the cryoprotectant solution and to suppress ice nucleation . Biological and clinical outcomes of SF protocols seem to be less than those obtained with fresh and vitrified oocytes [4, 5, 6]. Oocyte cryopreservation is usually used in ART laboratories for supernumerary oocyte storage after Controlled Ovarian Stimulation (COS) , prevention of Ovarian HyperStimulation Syndrome (OHSS) risk, oocyte...
KeywordsAssist Reproductive Technology Fertility Preservation Ovarian HyperStimulation Syndrome Embryo Cryopreservation Oocyte Cryopreservation
Conflict of interest
The Authors declare no potential conflict of interests.
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