Abstract
Previous reports of slow cooling of human mature oocytes have shown a reduced clinical efficiency relative to fresh oocytes. This study reports that equivalent fertilization and implantation rates to those obtained using fresh oocytes and cryopreserved embryos can be achieved with human mature oocytes dehydrated in 1.5 M propanediol and 0.2 M sucrose at 37°C and cryopreserved using slow cooling rates.
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Acknowledgement
We wish to thank the laboratory staff and medical team at Reproductive Services Royal Women’s Hospital and Melbourne IVF for their assistance with these cycles.
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Capsule Equivalent implantation rates for slow cooled mature oocytes dehydrated in 1.5 M propanediol and 0.2 M sucrose at 37°C and fresh oocytes from young women.
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Gook, D.A., Edgar, D.H. Implantation rates of embryos generated from slow cooled human oocytes from young women are comparable to those of fresh and frozen embryos from the same age group. J Assist Reprod Genet 28, 1171–1176 (2011). https://doi.org/10.1007/s10815-011-9678-6
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DOI: https://doi.org/10.1007/s10815-011-9678-6