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The utility of embryo banking in order to increase the number of embryos available for preimplantation genetic screening in advanced maternal age patients

  • Genetics
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Abstract

Purpose

To determine if embryo banking with PGS is more optimal than proceeding with PGS regardless of embryo number.

Methods

Patients were divided into 2 groups, group 1 were those that banked embryos and proceeded through another round of IVF prior to PGS, and group 2 underwent PGS regardless of embryo number. Group 2 was divided into group 2A (patients with >10 embryos) and group 2B (patients who had <10 embryos).

Results

There was no difference in embryos biopsied, normal embryos, number transferred, and pregnancy rate between group 1 and 2. A significant number of patients did not have a transfer in group 2B (6/11) compared to group 1 (3/19) (P = 0.0419). There was no significance between pregnancy rates per transfer between group 1 (6/16) and group 2B (2/5).

Conclusion

Our data suggests that banking will increase the odds of going to transfer but there was no increase in pregnancy rates.

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Correspondence to Tyl H. Taylor.

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Capsule

Banking embryos prior to PGS increases number of embryos to test and number normal in poor responders, but does not increase pregnancy rates.

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Orris, J.J., Taylor, T.H., Gilchrist, J.W. et al. The utility of embryo banking in order to increase the number of embryos available for preimplantation genetic screening in advanced maternal age patients. J Assist Reprod Genet 27, 729–733 (2010). https://doi.org/10.1007/s10815-010-9474-8

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  • DOI: https://doi.org/10.1007/s10815-010-9474-8

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