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A birth of twins—one boy and one girl—from a single embryo transfer and a possible natural pregnancy

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Abstract

Purpose

To describe a rare case of a birth of dizygotic twins with different-sex infants from a single embryo transfer.

Methods and results

A patient, who had her right ovary and tube removed, and her husband were treated with ICSI and a single embryo transfer. When a single fresh embryo was transferred on day 4, following oocyte retrieval using GnRH agonist-long protocol, two gestational sacs were recognized at 8 weeks of gestation. Healthy twins with a boy and a girl were delivered at 37 weeks 0 days of gestation by a cesarean section. The boy’s weight was 2096g, and his height was 45.0cm, while the girl’s weight was 1988g, and her height was 41.5cm. Peripheral lymphocyte chromosome analysis of the two infants showed normal karyotype, 46, XY (boy) and 46, XX (girl).

Conclusions

A single embryo transfer could produce different-sex twins.

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Author information

Authors and Affiliations

  1. Kyono ART Clinic, Mitsui-Seimei, Sendai Honcho Bld., 3F, 1-1-1, Honcho, Aobaku, Sendai, Miyagi, 980-0014, Japan

    Koichi Kyono, Yukiko Nakajo, Chikako Nishinaka, Masakazu Doshida, Mayumi Toya & Satoru Kanto

  2. The Institute for ARMT, 909-21, Ishii, Fujimi, Setagun, Gunma, 371-0105, Japan

    Yasuhisa Araki

Authors
  1. Koichi Kyono
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  2. Yukiko Nakajo
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  3. Chikako Nishinaka
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  4. Yasuhisa Araki
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  5. Masakazu Doshida
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  6. Mayumi Toya
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  7. Satoru Kanto
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Corresponding author

Correspondence to Koichi Kyono.

Additional information

Capsule A birth of dizygotic twins with different-sex infants from a single embryo transfer.

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Kyono, K., Nakajo, Y., Nishinaka, C. et al. A birth of twins—one boy and one girl—from a single embryo transfer and a possible natural pregnancy. J Assist Reprod Genet 26, 553–554 (2009). https://doi.org/10.1007/s10815-009-9348-0

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  • DOI: https://doi.org/10.1007/s10815-009-9348-0

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