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Previous tubal ectopic pregnancy raises the incidence of repeated ectopic pregnancies in In Vitro fertilization-embryo transfer patients

  • ASSISTED REPRODUCTION
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Abstract

Purpose

To investigate the incidence of Tubal Ectopic Pregnancies (TEP) in IVF-ET patients with respect to the status of the fallopian tubes after a previous TEP.

Material and methods

This retrospective study compares patients undergoing 481 IVF-ET cycles after conservatively or surgically treated TEP(s) with a Control Group (idiopathic or male factor for IVF-ET indication). Medical reports of surgery and/or hysterosalpingograms prior to the IVF cycles classified the status of the fallopian tubes.

Results

12 TEPs (8.95%/Pregnancies (PR)) occurred in the Study Group. In the Control Group one TEP (0.75%/PR; p < 0.001) was found. Smoking increased the probability of TEPs (p = 0.0028) and of pathological pregnancies (abortion, biochemical and ectopic PR; (p = 0.0411)). For statistic evolution logistic regression (PROC GENMOD) and a repeated measure model were applied.

Conclusion

Women with a previous TEP should be informed about the significantly increased risk for a further TEP in IVF-ET treatment, especially if they are smoking.

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Authors and Affiliations

  1. Wunschbabyzentrum, Lainzer Straße 6, A-1130, Vienna, Austria

    Monika Weigert & Wilfried Feichtinger

  2. Section of Medical Statistics, Core Unit for Medical Statistics and Informatics, Medical University of Vienna, Spitalgasse 23, A-1090, Vienna, Austria

    Diego Gruber, Elisabeth Pernicka & Peter Bauer

  3. Sampogasse 5/11, A-1140, Vienna, Austria

    Monika Weigert

Authors
  1. Monika Weigert
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  2. Diego Gruber
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  3. Elisabeth Pernicka
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  4. Peter Bauer
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  5. Wilfried Feichtinger
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Corresponding author

Correspondence to Monika Weigert.

Additional information

Capsule Tubes after a Tubal ectopic pregnancy (TEP) and smoking lead to a significant higher number of repeated TEPs in following IVF-ET programs.

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Weigert, M., Gruber, D., Pernicka, E. et al. Previous tubal ectopic pregnancy raises the incidence of repeated ectopic pregnancies in In Vitro fertilization-embryo transfer patients. J Assist Reprod Genet 26, 13–17 (2009). https://doi.org/10.1007/s10815-008-9278-2

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  • DOI: https://doi.org/10.1007/s10815-008-9278-2

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