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Reduction of perifollicular arterial blood flow resistance after hCG administration is a good indicator of the recovery of mature oocytes in ART treatment

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Journal of Assisted Reproduction and Genetics Aims and scope Submit manuscript

Abstract

Puerose: To demonstrate our hypothesis that a correlation exists between oocyte maturity and a decrease in intraovarian blood flow resistance in assisted reproductive technology (ART) treatment cycles, oocyte maturity and total antioxidant status (TAOS) in follicular fluid was examined.

Methods: A total of 59 cycles involving 51 infertile patients undergoing ART treatment in our hospital were recruited in this study. The ART cycles were divided into two groups: deeply decreased (DD) group and not-deeply decreased (NDD) group, according to the pulsatility index (PI) values for perifollicular arterial blood flow before and after hCG administration. The PI values that showed a decrease in their PI after hCG administration of 10% or more were defined “deeply decreased” and showed a decrease of less than 10% were considered “not-deeply decreased.” The recovery rates of mature and immature oocytes and TAOS in follicular fluid were compared between the two groups.

Results: Mature and immature oocyte recovery rates in the DD group (62.5% and 17.2%) were significantly higher and lower, respectively, than those in the NDD group (41.7% and 38.3%, p < 0.05). The TAOS (1.55 ± 0.44 mmol/L) of the DD group was significantly lower than that in the NDD group (1.68 ± 0.47 mmol/L, p < 0.05).

Conclusions: The decrease in intraovarian arterial blood flow resistance measured after hCG administration may be a good indicator of retrieving mature oocyte.

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Authors and Affiliations

  1. Division of Reproductive Medicine, Department of Perinatal Medicine and Maternal Care, National Center for Child Health and Development, 2-10-1 Okura, Setagaya, Tokyo, 157-8535, Japan

    Koji Nakagawa, Shirei Ohgi, Rieko Kojima, Megumu Itoh, Takashi Horikawa & Hidekazu Saito

  2. Department of Obstetrics and Gynecology, School of Medicine, The University of Tokushima, Tokushima, Japan

    Minoru Irahara

Authors
  1. Koji Nakagawa
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  2. Shirei Ohgi
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  3. Rieko Kojima
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  4. Megumu Itoh
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  5. Takashi Horikawa
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  6. Minoru Irahara
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  7. Hidekazu Saito
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Correspondence to Koji Nakagawa.

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Nakagawa, K., Ohgi, S., Kojima, R. et al. Reduction of perifollicular arterial blood flow resistance after hCG administration is a good indicator of the recovery of mature oocytes in ART treatment. J Assist Reprod Genet 23, 433–438 (2006). https://doi.org/10.1007/s10815-006-9087-4

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  • DOI: https://doi.org/10.1007/s10815-006-9087-4

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