Intracytoplasmic sperm injection (ICSI) in unexplained and stage I endometriosis-associated infertility after fertilization failure with in vitro fertilization (IVF)

  • Anne K. OmlandEmail author
  • Sverre Bjercke
  • Gudvor Ertzeid
  • Peter Fedorcsák
  • Nan B. Oldereid
  • Ritsa Storeng
  • Thomas Åbyholm
  • Tom Tanbo
Original Paper


Purpose: To investigate possible differences between unexplained and stage I endometriosis-associated infertility in ICSI cycles conducted after low fertilization (<20%) in preceding IVF cycles with normal semen parameters.

Methods: Retrospective cohort study consisting of patients with unexplained (n=48) and stage I endometriosis-associated infertility (n=43) with a minimum of one IVF cycle with <20% fertilized oocytes and normal semen quality, treated with ICSI from January 1997 to January 2006. Age matched male factor infertility patients (n=91) were used as controls.

Results: Diploid fertilization rate was significantly lower in the stage I endometriosis-associated infertility group compared to the unexplained infertility group. Score of the transferred embryos, implantation rate, pregnancy rate and outcome were similar in the two groups.

Conclusions: ICSI appears to be an efficient treatment option after fertilization failure with IVF in unexplained and stage I endometriosis-associated infertility.


Endometriosis Fertilization failure ICSI IVF Unexplained infertility 


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Copyright information

© Springer Science&#x002B;Business Media, Inc. 2006

Authors and Affiliations

  • Anne K. Omland
    • 1
    Email author
  • Sverre Bjercke
    • 1
  • Gudvor Ertzeid
    • 1
  • Peter Fedorcsák
    • 1
  • Nan B. Oldereid
    • 1
  • Ritsa Storeng
    • 1
  • Thomas Åbyholm
    • 1
  • Tom Tanbo
    • 1
  1. 1.Department of Obstetrics and GynaecologyRikshospitalet–Radiumhospitalet Medical CenterOsloNorway

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