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Journal of Applied Spectroscopy

, Volume 81, Issue 1, pp 140–144 | Cite as

Application of Electron Paramagnetic Resonance to Study of Gallstones

  • S. A. Kiselev
  • L. V. Tsyro
  • D. A. Afanasiev
  • F. G. Unger
  • M. M. Soloviev
Article

We present the results of an electron paramagnetic resonance (EPR) study of mixed cholesterol gallstones. We have established that free radicals are distributed nonuniformly within the interior of the stone. The type and number of paramagnetic centers depend on the pigment content in the selected layer. We show that the parameters of the sextet lines in the EPR spectrum of the pigment are close to the parameters of lines in the spectrum of a brown pigment stone.

Keywords

electron paramagnetic resonance free radicals mixed gallstones cholesterol gallstones bilirubin 

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References

  1. 1.
    F. G. Unger, L. V. Tsyro, L. N. Andreeva, S. Ya. Aleksandrova, D. A. Afanas’ev, S. A. Kiselev, F. F. Sannikov, A. F. Unger, M. F. Unger, and A. K. Éfa, in: Nanosystems, Disperse Systems, Quantum Mechanics, and Spin Chemistry [in Russian], TML-Press, Tomsk (2010), pp. 205–249.Google Scholar
  2. 2.
    W. Droge, Phys. Rev., 82, 47–95 (2002).Google Scholar
  3. 3.
    T. W. Kensler and M. A. Trush, Environ. Mutagen., 6, 593–616 (1984).CrossRefGoogle Scholar
  4. 4.
    P. A. Southorn and G. Powis, Cell Chem. Physiol., 4, No. 2, 357–371 (1996).Google Scholar
  5. 5.
    M. Martinez-Cayuela, Biochim., 77, 147–161 (1995).CrossRefGoogle Scholar
  6. 6.
    R. Stocker, A. F. McDonagh, A. N. Glazer, and B. N. Ames, Method. Enzymol., 186, 301–309 (1990).CrossRefGoogle Scholar
  7. 7.
    L. B. Dudnik and N. G. Khrapova, Membr. Cell Biol., 12, No. 2, 233–240 (1998).Google Scholar
  8. 8.
    R. Stocker, Y. Yamamoto, A. F. McDonagh, A. N. Glazer, and B. N. Ames, Science, 235, 1043–1045 (1987).ADSCrossRefGoogle Scholar
  9. 9.
    L. Xiang-Tao and H. Jian, World J. Gastroenterol., 8, No. 3, 413–417 (2002).Google Scholar
  10. 10.
    G. Elek and A. Rockenbauer, Klinisch. Wochenschrift, 60, 33–35 (1982).CrossRefGoogle Scholar
  11. 11.
    O. A. Golovanova, Biomineralogy of Uroliths, Gallstones, Dental Plaque, and Salivary Calculi from the Human Body, Author’s Abstract, Dissertation in competition for the academic degree of Doctor of Geology/Mineralogy, Tomsk (2009).Google Scholar
  12. 12.
    É. I. Beloborodova, in: Selected Chapters in Clinical Gastroenterology [in Russian], NTL, Tomsk (2002), Part 2, pp. 50–65.Google Scholar
  13. 13.
    P. M. Bills and D. A. Lewis, Gut, 16, 630–637 (1975).CrossRefGoogle Scholar
  14. 14.
    E. N. Chikvaidze, T. V. Gogoladze, I. N. Kirikashvili, and G. I. Mamniashvili, Georg. Med. News, 168, 10–14 (2009).Google Scholar
  15. 15.
    W. Chua-Anusorn, T. G. St. Pierre, J. Webb, K. Wang, and J. F. Lu, Hyperfine Interact., 91, 911–916 (1994).ADSCrossRefGoogle Scholar
  16. 16.
    P. F. Malet, C. E. Williamson, B. W. Trotman, and R. D. Soloway, Hepatology, 6, No. 3, 477–481 (1986).CrossRefGoogle Scholar
  17. 17.
    D. J. Sutor and S. E. Wooley, Gut, 15, 130–131 (1974).CrossRefGoogle Scholar
  18. 18.
    J. Donald Ostrow, Hepatology, 4, No. 5, 215–221 (1984).CrossRefGoogle Scholar
  19. 19.
    M. Stefan, S. V. Nistor, and J. N. Barascu, J. Magn. Res., 210, 200–209 (2011).Google Scholar
  20. 20.
    B. Bleaney and R. S. Rubins, Proc. Phys. Soc., 77, 103–112 (1961).ADSCrossRefGoogle Scholar
  21. 21.
    L. N. Andreeva, S. Ya. Aleksandrova, L. V. Tsyro, and F. G. Unger, Izv. Vuzov. Neft’ Gaz, 4, 101–107 (2009).Google Scholar
  22. 22.
    L. N. Andreeva, L. V. Tsyro, S. Ya. Aleksandrova, A. Yu. Potachkina, M. V. Tikhonova, and F. G. Unger, Izv. Vuzov. Neft’ Gaz, 1, 63–69 (2008).Google Scholar
  23. 23.
    L. N. Andreeva, S. Ya. Aleksandrova, L. V. Tsyro, and F. G. Unger, Tekhnol. Topl.-Énerg. Kompleksa, 6, 74–79 (2007).Google Scholar
  24. 24.
    L. N. Andreeva, L. V. Tsyro, S. Ya. Aleksandrova, and F. G. Unger, Tekhnol. Topl.-Énerg. Kompleksa, 5, 98–103 (2003).Google Scholar
  25. 25.
    L. V. Tsyro, L. N. Andreeva, S. Ya. Aleksandrova, and F. G. Unger, Voda: Khimiya Ékologiya, 4, 66–73 (2011).Google Scholar
  26. 26.
    F. G. Unger, L. V. Tsyro, M. V. Tikhonova, S. Ya. Aleksandrova, D. A. Afanas’ev, A. F. Unger, and L. N. Andreeva, Polzunovsk. Vestn., 3, 77–81 (2009).Google Scholar

Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • S. A. Kiselev
    • 1
  • L. V. Tsyro
    • 1
  • D. A. Afanasiev
    • 1
  • F. G. Unger
    • 1
  • M. M. Soloviev
    • 2
  1. 1.National Research Tomsk State UniversityTomskRussia
  2. 2.Siberian State Medical UniversityTomskRussia

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