Journal of Applied Spectroscopy

, Volume 79, Issue 3, pp 446–452 | Cite as

Effect of extracorporeal ultraviolet blood irradiation on blood cholesterol level

  • G. A. Zalesskaya
  • O. V. Laskina
  • N. P. Mitkovskaya
  • V. V. Kirkovsky

We have studied the effect of extracorporeal ultraviolet blood irradiation on cholesterol metabolism in patients with cardiovascular diseases. We have carried out a comprehensive analysis of the spectral characteristics of blood and plasma, gas-exchange and oximetry parameters, and the results of a complete blood count and chemistry panel before and after UV blood irradiation. We have assessed the changes in concentrations of cholesterols (total cholesterol, low-density lipoprotein (LDL) cholesterol, triglycerides) in the blood of the patients in response to a five-day course of UV blood irradiation. The changes in the spectral characteristics of blood and plasma, the chemistry panel, the gas composition, and the fractional hemoglobin composition initiated by absorption of UV radiation are used to discuss the molecular mechanisms for the effect of therapeutic doses of UV radiation on blood cholesterols.


ultraviolet blood irradiation absorption spectra of blood and plasma in the UV-visible and IR ranges cholesterol low-density lipoprotein (LDL) cholesterol level of hemoglobin oxygen saturation active oxygen species 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    E. Knott, Am. J. Surgery, 76, No. 2, 165–171 (1948).CrossRefGoogle Scholar
  2. 2.
    V. I. Karandashov and E. B. Petukhov, Ultraviolet Blood Irradiation [in Russian], Meditsina, Moscow (1997).Google Scholar
  3. 3.
    I. G. Dutkevich, G. V. Golovin, K. A. Samoilova, and Yu. P. Popov, in: Mechanisms for the Effect of UV-Irradiated Blood on the Human Body and in Animals [in Russian], Nauka, Leningrad (1986), pp. 18–25.Google Scholar
  4. 4.
    D. I. Roshchupkin and M. A. Murina, Biofizika, 38, No. 6, 1053–1068 (1993).Google Scholar
  5. 5.
    Yu. A. Vladimirov and A. I. Archakov, Lipid Peroxidation in Biological Membranes [in Russian], Nauka, Moscow (1972).Google Scholar
  6. 6.
    U. P. Steibrecher, S. Parthasarathy, D. S. Leake, J. L. Witztum, and D. Steinberg, Proc. Nat. Acad. Sci., 81, 3383–3387 (1984).Google Scholar
  7. 7.
    Kan-Zhi Liu, R. A. Shaw, A. Man, T. C. Dembinski, and N. N. Mantsch, Clinic. Chem., 48, 499–506 (2002).Google Scholar
  8. 8.
    G. A. Zalesskaya and V. S. Ulashchik, Zh. Prikl. Spektrosk., 76, No. 1, 51–75 (2009).Google Scholar
  9. 9.
    G. A. Zalesskaya, V. S. Ulashchik, and I. I. Kalosha, Opt. Spektrosk., 107, No. 4, 695–702 (2009).CrossRefGoogle Scholar
  10. 10.
    G. A. Zalesskaya and T. O. Maslova, Opt. Spektrosk., 109, 337-343 (2011).Google Scholar
  11. 11.
    N. K. Zenkov, V. Z. Lankin, and E. B. Men’shchikova, Oxidative Stress: Biochemical and Pathophysiological Aspects [in Russian], Nauka/Interperiodika, Moscow (2001).Google Scholar

Copyright information

© Springer Science+Business Media, Inc. 2012

Authors and Affiliations

  • G. A. Zalesskaya
    • 1
  • O. V. Laskina
    • 2
  • N. P. Mitkovskaya
    • 2
  • V. V. Kirkovsky
    • 2
  1. 1.B. I. Stepanov Institute of PhysicsNational Academy of Sciences of BelarusMinskBelarus
  2. 2.Belorussian State Medical UniversityMinskBelarus

Personalised recommendations